产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
抗TLR7抗体
目录 :
MBS8291483
规格 :
0.05毫升
价格 :
175美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学
更多信息或购买 :
MyBioSource 产品网页
图像
图像 1 :
MyBioSource MBS8291483 图像 1
Western blot analysis of TLR7 expression in Ramos (A) whole cell lysates.
图像 2 :
MyBioSource MBS8291483 图像 2
Immunofluorescent analysis of TLR7 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
产品信息
目录号 :
MBS8291483
产品类型 :
抗体
产品全称 :
抗TLR7抗体
产品简称 :
[TLR7]
产品名称同义词 :
[Toll样受体7]
其他名称 :
[Toll样受体7;Toll样受体7;Toll样受体7;Toll样受体7]
产品基因名称 :
[TLR7]
其他基因名称 :
[TLR7; TLR7; TLR7-like]
克隆性 :
多克隆
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
1049
特异性 :
Recognizes endogenous levels of TLR7 protein.
纯度 :
The antibody was purified by immunogen affinity chromatography.
形式 :
液体0.42% 钾磷酸盐, 0.87% 氯化钠, pH值7.3, 30% 甘油, 和0.01% 叠氮化钠
储存稳定性 :
Shipping: Blue Ice. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
检测过的应用 :
免疫印迹(免疫印迹), 免疫荧光(IF), 免疫细胞化学(免疫细胞化学)
应用笔记 :
WB: 1/500 - 1/2000。 IF/ICC: 1/50 - 1/200
image1头 :
免疫印迹(免疫印迹)
image2头 :
免疫荧光(IF)
其它信息1 :
Immunogen: Recombinant full length protein of human TLR7
产品描述 :
兔多克隆抗体TLR7
NCBI GI登录号 :
7706093
NCBI登录号 :
NP_057646.1
NCBI基因登录号 :
NM_016562.3
UniProt数据库登录号 :
Q9NYK1
NCBI信号通路 :
Immune System Pathway (106386); Influenza A Pathway (217173); Influenza A Pathway (217150); Innate Immune System Pathway (106387); Measles Pathway (213306); Measles Pathway (213277); MyD88 Dependent Cascade Initiated On Endosome Pathway (187081); TRAF6 Mediated IRF7 Activation In TLR7/8 Or 9 Signaling Pathway (187085); TRAF6 Mediated Induction Of NFkB And MAP Kinases Upon TLR7/8 Or 9 Activation Pathway (187082); Toll Like Receptor 7/8 (TLR7/8) Cascade Pathway (106396)
NCBI总结 :
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response ().
尺寸1 :
0.05毫升
价格1 :
175美元
尺寸2 :
0.1毫升
价格2 :
220
size3 :
0.2毫升
价格3 :
295
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。