抗体

SYP抗体

MBS830146

5毫升

285美元

单克隆

小鼠

未共轭

[SY38]

人类, 小鼠, 大鼠, 牛

免疫印迹, 免疫组化, 免疫细胞化学

抗体

SYP抗体

[SYP]

[单克隆突触素;抗突触素;SYP;突触素]

[synaptophysin; Synaptophysin; synaptophysin; synaptophysin; BM89 antigen; Major synaptic vesicle protein p38]

[SYP]

[Syp; Syp; Syn; p38; AI848995; A230093K24Rik]

SYPH_MOUSE

单克隆

IgG1

[SY38]

小鼠

牛, 人类, 小鼠, 大鼠

314

牛突触素

Hybridoma cell culture supernatant containing 0.09% Sodium Azide.

Ships ambient or refrigerated. Upon receipt store at 4°C or aliquot and freeze at -20°C. Avoid repeat freeze/thaw cycles.

免疫荧光(IF), 免疫组化(免疫组化), 免疫印迹(免疫印迹)

Optimal conditions to be determined by end user.

Biological Significance: Synaptophysin is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38kDa. It is present in neuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for neuroendocrine tumors, and its ubiquity at the synapse has led to the use of synaptophysin immunostaining for quantification of synapses.

Immunogen: Synaptophysin from presynaptic vesicles, prepared from bovine brain.

Cancer

小鼠单克隆SYP抗体

166235165

NP_033331.2

NM_009305.2

SYP: Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity. Homohexamer or homotetramer. Interacts with SRCIN1. Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype. Belongs to the synaptophysin/synaptobrevin family. Protein type: Vesicle; Membrane protein, integral; Membrane protein, multi-pass. Cellular Component: neuron projection; protein complex; synaptic vesicle membrane; integral to membrane; terminal button; excitatory synapse; intracellular organelle; integral to synaptic vesicle membrane; presynaptic membrane; synaptic vesicle; membrane; presynaptic active zone; synapse; cytoplasmic vesicle; cell junction. Molecular Function: identical protein binding; protein domain specific binding; protein binding; transporter activity; protein complex binding; cholesterol binding; syntaxin-1 binding; SH2 domain binding. Biological Process: regulation of long-term neuronal synaptic plasticity; synaptic transmission; transport; endocytosis; regulation of short-term neuronal synaptic plasticity; regulation of neuronal synaptic plasticity

5毫升

285美元