产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
CCL5抗体
目录 :
MBS832494
规格 :
0.1毫克
价格 :
370美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, ,
应用 :
免疫印迹
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS832494 图像 1
Western Blot analysis using CCL5 antibody. CCL5 antibody used at 1.25 ug/ml to detect target protein.
产品信息
目录号 :
MBS832494
产品类型 :
抗体
产品全称 :
CCL5抗体
产品简称 :
[CCL5]
产品名称同义词 :
[Polyclonal CCL5 antibody, Anti-CCL5 antibody, CCL-5 antibody, CCL 5, CCL5, CCL-5, Chemokine (C-C motif) ligand 5 antibody, CCL 5 antibody]
其他名称 :
[C-C motif chemokine 5; C-C motif chemokine 5; C-C motif chemokine 5; chemokine (C-C motif) ligand 5; MuRantes; SIS-delta; Small-inducible cytokine A5; T-cell-specific protein RANTES]
产品基因名称 :
[CCL5]
其他基因名称 :
[Ccl5; Ccl5; SISd; Scya5; RANTES; TCP228; MuRantes; Scya5]
UniProt数据库进入名 :
CCL5_MOUSE
克隆性 :
多克隆
宿主 :
反应物种 :
牛, 狗, 豚鼠, 马, 人类, 小鼠, 猪, 兔, 大鼠
序列长度 :
91
形式 :
Liquid in PBS buffer with 0.09% NaN 3 , and 2% Sucrose.
浓度 :
1毫克/毫升
储存稳定性 :
Store at 4°C for short term, -20°C for long term. Avoid repeat freeze-thaws.
检测过的应用 :
适合用途包括免疫印迹(免疫印迹)
应用笔记 :
WB:1.25微克/毫升
image1头 :
免疫印迹
其它信息1 :
Biological Significance: Recently, it has been shown that genetic polymorphisms can result in diminished expression of CCL5, which results in increased susceptibility to and progression of infectious diseases. CCL5, together with Th cytokine mRNA expression, is temporally up-regulated during pneumococcal carriage. CCL5 is an essential factor for the induction and maintenance of protective pneumococcal immunity
其他信息2 :
Immunogen: Synthetic peptide directed towards the middle region of mouse CCL5.
产品种类 :
细胞因子&生长因子
产品描述 :
兔多克隆CCL5抗体
NCBI GI登录号 :
164698428
NCBI登录号 :
NP_038681
NCBI基因登录号 :
NM_013653.3
UniProt数据库登录号 :
P30882
NCBI信号通路 :
Chagas Disease (American Trypanosomiasis) Pathway (147810); Chagas Disease (American Trypanosomiasis) Pathway (147795); Chemokine Receptors Bind Chemokines Pathway (1168363); Chemokine Signaling Pathway (99271); Chemokine Signaling Pathway (672435); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (1168361); Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Cytosolic DNA-sensing Pathway (125146)
UniProt数据库总结 :
CCL5: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. Binds to CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T- cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils. By mitogens. T-cell and macrophage specific. Belongs to the intercrine beta (chemokine CC) family. Protein type: Cell adhesion; Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis; Chemokine. Cellular Component: extracellular space; cell; cytoplasm; extracellular region; intracellular. Molecular Function: heparin binding; protein homodimerization activity; protein self-association; cytokine activity; receptor signaling protein tyrosine kinase activator activity; phosphoinositide phospholipase C activity; protein kinase activity; CCR1 chemokine receptor binding; chemokine activity; chemokine receptor binding; chemokine receptor antagonist activity; phospholipase activator activity; chemoattractant activity; CCR5 chemokine receptor binding. Biological Process: exocytosis; positive regulation of cell adhesion; positive regulation of osteoclast differentiation; positive regulation of smooth muscle cell proliferation; response to toxin; positive regulation of smooth muscle cell migration; chemotaxis; positive regulation of cell-cell adhesion mediated by integrin; protein amino acid phosphorylation; pseudopodium formation; positive regulation of homotypic cell-cell adhesion; leukocyte adhesion; cell-cell signaling; positive chemotaxis; calcium ion transport; lipopolysaccharide-mediated signaling pathway; protein kinase B signaling cascade; positive regulation of T cell proliferation; inflammatory response; lymphocyte chemotaxis; protein tetramerization; phospholipase D activation; neutrophil activation; negative regulation of G-protein coupled receptor protein signaling pathway; MAPKKK cascade; positive regulation of cellular biosynthetic process; cellular calcium ion homeostasis; positive regulation of phosphoinositide 3-kinase cascade; G-protein coupled receptor protein signaling pathway; positive regulation of angiogenesis; cellular protein complex assembly; positive regulation of tyrosine phosphorylation of STAT protein; negative regulation of viral genome replication; response to cytokine stimulus; eosinophil chemotaxis; positive regulation of fever; immune response; positive regulation of calcium ion transport; positive regulation of neuron differentiation; positive regulation of defense response to virus by host; regulation of insulin secretion; positive regulation of epithelial cell proliferation; positive regulation of phosphorylation; regulation of T cell activation; positive regulation of cell migration
尺寸1 :
0.1毫克
价格1 :
370美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。