产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
转铁蛋白抗体
目录 :
MBS835722
规格 :
10毫升
价格 :
245美元
克隆性 :
多克隆
宿主 :
山羊
共轭标签 :
未共轭
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
MBS835722
产品类型 :
抗体
产品全称 :
转铁蛋白抗体
产品简称 :
转铁蛋白
产品名称同义词 :
Polyclonal Transferrin; Anti-Transferrin; Siderophilin; PRO1557; PRO1400; TF; DKFZp781D0156; Serotransferrin precursor; Apotransferrin; Beta 1 metal binding globulin; PRO2086
其他名称 :
transferrin; Serotransferrin; serotransferrin; transferrin; Beta-1 metal-binding globulin; Siderophilin
其他基因名称 :
TF;TF;TFQTL1;PRO1557;PRO2086;转铁蛋白
UniProt数据库进入名 :
TRFE_HUMAN
克隆性 :
多克隆
宿主 :
山羊
反应物种 :
Monospecific for Human Transferrin.
序列长度 :
698
特异性 :
人类
形式 :
Supplied as an IgG Fracton, delipidated, defibrinated and 0.2 um filtered in 0.2M Tris, 0.5M NaCl, pH 7.2 with 0.08% NaN3.
储存稳定性 :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
检测过的应用 :
User optimized
其它信息1 :
Biological Significance: Transferrins are iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids. In humans, it is encoded by the TF gene. Transferrin is a glycoprotein that binds iron very tightly but reversibly. Although iron bound to transferrin is less than 0.1% (4 mg) of the total body iron, it is the most important iron pool, with the highest rate of turnover (25 mg/24 h).
其他信息2 :
Immunogen: Transferrin antibody was raised in goat using transferrin from normal human plasma as the immunogen.
产品种类 :
细胞生物学
产品描述 :
多克隆转铁蛋白抗体
NCBI GI登录号 :
248648
NCBI登录号 :
AAB22049.1
UniProt数据库登录号 :
P02787
NCBI分子量 :
77,064 Da
NCBI信号通路 :
EPHB Forward Signaling Pathway (138047); HIF-1 Signaling Pathway (695200); HIF-1-alpha Transcription Factor Network Pathway (138045); Hemostasis Pathway (106028); Iron Metabolism In Placenta Pathway (672461); Iron Uptake And Transport Pathway (187191); Mineral Absorption Pathway (212237); Mineral Absorption Pathway (212220); Platelet Activation, Signaling And Aggregation Pathway (106034); Platelet Degranulation Pathway (106050)
NCBI总结 :
This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]
UniProt数据库总结 :
TF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Defects in TF are the cause of atransferrinemia (ATRAF). Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. Belongs to the transferrin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3q22.1. Cellular Component: extracellular space; cell surface; early endosome; cytoplasmic membrane-bound vesicle; extracellular region; coated pit; recycling endosome; endocytic vesicle; perinuclear region of cytoplasm; late endosome; apical plasma membrane; basal plasma membrane; endosome membrane; vesicle. Molecular Function: protein binding; ferric iron binding; ubiquitin protein ligase binding. Biological Process: retinal homeostasis; platelet activation; platelet degranulation; cellular iron ion homeostasis; transferrin transport; blood coagulation; transmembrane transport. Disease: Atransferrinemia
尺寸1 :
10毫升
价格1 :
245美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。