产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
PRCP抗体
目录 :
MBS8502445
规格 :
0.1毫克
价格 :
300美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 酶免疫法
更多信息或购买 :
产品信息
目录号 :
MBS8502445
产品类型 :
抗体
产品全称 :
PRCP抗体
产品简称 :
[PRCP]
其他名称 :
[lysosomal Pro-X carboxypeptidase isoform 1 preproprotein; Lysosomal Pro-X carboxypeptidase; lysosomal Pro-X carboxypeptidase; prolylcarboxypeptidase; Angiotensinase C; Lysosomal carboxypeptidase C; Proline carboxypeptidase; Prolylcarboxypeptidase; PRCP]
产品基因名称 :
[PRCP]
其他基因名称 :
[PRCP;PRCP;PCP;HUMPCP;PCP;PRCP]
克隆性 :
多克隆
宿主 :
兔
反应物种 :
人类, 小鼠
序列长度 :
496
特异性 :
PCP多克隆抗体检测内生水平蛋白
纯度 :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
形式 :
液体PBS, 含50% 甘油, 和0.02% 叠氮化钠
浓度 :
1毫克/毫升, 100微升
储存稳定性 :
Store at -20°C/ 1 year.
检测过的应用 :
免疫印迹(免疫印迹), 酶联免疫吸附测定(EIA)
应用笔记 :
WB: 1:500-2000。 ELISA: 1:5000-20000
其它信息1 :
Signal Pathway: 54. Observed Band (KDa): 54
NCBI GI登录号 :
4826940
NCBI登录号 :
NP_005031.1
NCBI基因登录号 :
NM_005040.3
UniProt数据库登录号 :
P42785
NCBI信号通路 :
Formation Of Fibrin Clot (Clotting Cascade) Pathway (106057); Hemostasis Pathway (106028); Intrinsic Pathway (106059); Protein Digestion And Absorption Pathway (172847); Protein Digestion And Absorption Pathway (171868)
NCBI总结 :
This gene encodes a member of the peptidase S28 family of serine exopeptidases. The encoded preproprotein is proteolytically processed to generate the mature lysosomal prolylcarboxypeptidase. This enzyme cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. A pseudogene of this gene has been identified on chromosome 2. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
UniProt数据库总结 :
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
尺寸1 :
0.1毫克
价格1 :
300美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。