产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
CD44抗体
目录 :
MBS850417
规格 :
0.1毫克
价格 :
280美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
[8E2F3]
反应物种 :
人类, 小鼠
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS850417 图像 1
Figure 1. Western blot analysis using CD44 mouse mAb against truncated Trx-CD44 recombinant protein (1) and GST-CD44 (aa628-699) recombinant protein (2).
图像 2 :
MyBioSource MBS850417 图像 2
Figure 2. Western blot analysis using CD44 mouse mAb against Hela (1) and HUVE-12(2) cell lysate.
图像 3 :
MyBioSource MBS850417 图像 3
Figure 3. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissues, showing membrane localization with DAB staining using CD44 mouse mAb.
产品信息
目录号 :
MBS850417
产品类型 :
抗体
产品全称 :
CD44抗体
产品简称 :
[CD44]
产品名称同义词 :
[在;LHR;MC56;MDU2;MDU3;MIC4;Pgp1;CDW44;CSPG8;HCELL]
其他名称 :
[CD44 antigen isoform 1; CD44 antigen; CD44 antigen; CD44 molecule (Indian blood group); CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; CD_antigen: CD44]
产品基因名称 :
[CD44]
其他基因名称 :
[CD44;CD44;在;LHR;MC56;MDU2;MDU3;MIC4;Pgp1;CDW44;CSPG8;HCELL;HUTCH-I;ECMR-III;LHR;MDU2;MDU3;MIC4;ECMR-III;PGP-1;PGP-I]
克隆性 :
m
抗体亚型 :
IgG1
克隆 :
[8E2F3]
宿主 :
小鼠
反应物种 :
人类, 小鼠
序列长度 :
742
形式 :
腹水含0.03% 叠氮化钠
储存稳定性 :
存放在4°C, 为长期储存, 存放在-20°C
检测过的应用 :
免疫印迹(免疫印迹), 免疫组化(免疫组化), 免疫荧光(IF), 酶联免疫吸附测定(EIA)。 尚未在其他应用中测试
应用笔记 :
Determining optimal working dilutions by titrations test. WB: 1:500-1:2000. IF: 1:200-1:1000. ELISA. Propose dilution 1:10000.
image1头 :
免疫印迹(免疫印迹)
image2头 :
免疫印迹(免疫印迹)
image3头 :
免疫组化(免疫组化)
其它信息1 :
Immunogen: Purified recombinant fragment of human CD44 (628-699) expressed in E. Coli.
产品种类 :
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
产品描述 :
CD44, also known as IN, LHRMIC4, CDW44, HCELL. It is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
NCBI GI登录号 :
48255935
NCBI登录号 :
NP_000601.3
NCBI基因登录号 :
NM_000610.3
UniProt数据库登录号 :
P16070
NCBI分子量 :
82kDa
NCBI信号通路 :
Cytokine Signaling In Immune System Pathway (366171); Disease Pathway (530764); ECM-receptor Interaction Pathway (83068); ECM-receptor Interaction Pathway (479); Epstein-Barr Virus Infection Pathway (585562); Epstein-Barr Virus Infection Pathway (587115); Glycosaminoglycan Metabolism Pathway (645297); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Hyaluronan Metabolism Pathway (645298)
NCBI总结 :
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function ().
尺寸1 :
0.1毫克
价格1 :
280美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。