MyBioSource

抗体

AGT抗体

MBS850936

0.1毫克

290美元

单克隆

小鼠

免疫印迹, 酶联免疫吸附测定, 酶免疫法

MBS850936

抗体

AGT抗体

AGT

ANHU

angiotensinogen preproprotein; Angiotensinogen; angiotensinogen; serpin A8; angiotensin I; angiotensin II; pre-angiotensinogen; alpha-1 antiproteinase, antitrypsin; serine (or cysteine) proteinase inhibitor; angiotensinogen (serpin peptidase inhibitor, clade A, member 8); Serpin A8Cleaved into the following 8 chains:Angiotensin-1Alternative name(s):Angiotensin 1-10; Angiotensin I; Ang I

AGT

AGT; AGT; ANHU; SERPINA8; SERPINA8; Ang I; Ang II; Ang III; Ang IV

ANGT_HUMAN

单克隆

1B1

小鼠

人类

485

腹水含0.03% 叠氮化钠

100微克/100微升

Store at 4 degree C. For long term storage, store at -20 degree C

免疫印迹(免疫印迹), 酶联免疫吸附测定(EIA)

WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000. Not yet tested in other applications. Determining optimal working dilutions by titration test.

Immunogen: Purified recombinant fragment of human AGT expressed in E. Coli. Species: Mouse IgG2b

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

Background: AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

4557287

NP_000020.1

NM_000029.3

53kDa

ACE Inhibitor Pathway 198763!!Adipogenesis Pathway 198832!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!G Alpha (i) Signalling Events Pathway 119550!!G Alpha (q) Signalling Events Pathway 106043!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!Gastrin-CREB Signalling Pathway Via PKC And MAPK 645295!!Metabolism Pathway 477135

The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]

0.1毫克

290美元