产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
白细胞介素-8抗体
目录 :
MBS851070
规格 :
0.1毫克
价格 :
290美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 酶免疫法
更多信息或购买 :
产品信息
目录号 :
MBS851070
产品类型 :
抗体
产品全称 :
白细胞介素-8抗体
产品简称 :
白细胞介素-8
其他名称 :
IL8, partial; Interleukin-8; interleukin-8; emoctakin; interleukin 8; T-cell chemotactic factor; neutrophil-activating peptide 1; beta-thromboglobulin-like protein; granulocyte chemotactic protein 1; tumor necrosis factor-induced gene 1; alveolar macrophage chemotactic factor I; monocyte-derived neutrophil chemotactic factor; monocyte-derived neutrophil-activating peptide; small inducible cytokine subfamily B, member 8; lymphocyte derived neutrophil activating peptide; lung giant cell carcinoma-derived chemotactic protein; beta endothelial cell-derived neutrophil activating peptide; chemokine (C-X-C motif) ligand 8; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factorCleaved into the following 7 chains:MDNCF-aAlternative name(s):GCP/IL-8 protein IV; IL8/NAP1 form I
产品基因名称 :
白细胞介素-8
其他基因名称 :
CXCL8;CXCL8;白细胞介素-8;NAF;GCP1;LECT;LUCT;NAP1;GCP-1;LYNAP;MDNCF;MONAP;NAP-1;白细胞介素-8;IL-8;GCP-1;MDNCF;MONAP;NAP-1;LYNAP;NAF
UniProt数据库进入名 :
IL8_HUMAN
克隆性 :
多克隆
宿主 :
反应物种 :
人类
序列长度 :
99
形式 :
Lyophilized IL8 antibody purified by protein affinity column containing 0.02% NaN3
浓度 :
100微克/200微升
储存稳定性 :
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
检测过的应用 :
免疫印迹(免疫印迹), 酶联免疫吸附测定(EIA), 免疫组化(免疫组化)
应用笔记 :
ELISA titer: 1:20,000-1:80,000. Western blot analysis: 1:500-1:1,000. Immunohistochemistry: 1:100-1:500. Optimal dilutions/concentrations should be determined by the end user.
其它信息1 :
Source Note: Rabbit polyclonal IL8(1) antibody was raised against a recombinate human IL8 protein 21-99aa (BC013615). Reactivity Note: Predicted: Mouse, Rat; Not yet tested in other species.
产品种类 :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
NCBI GI登录号 :
49457298
NCBI登录号 :
CAG46948.1
UniProt数据库登录号 :
P10145
NCBI分子量 :
11,338 Da
NCBI信号通路 :
ATF-2 Transcription Factor Network Pathway (138006); ATF4 Activates Genes Pathway (530772); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Bladder Cancer Pathway (83115); Bladder Cancer Pathway (527); Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway (137993); Cellular Senescence Pathway (905991); Cellular Responses To Stress Pathway (645258); Chagas Disease (American Trypanosomiasis) Pathway (147809)
NCBI总结 :
The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
IL8: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. Belongs to the intercrine alpha (chemokine CxC) family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis; Cytokine. Chromosomal Location of Human Ortholog: 4q13-q21. Cellular Component: extracellular space; extracellular region. Molecular Function: protein binding; chemokine activity; interleukin-8 receptor binding. Biological Process: regulation of cell adhesion; neutrophil chemotaxis; neutrophil activation; negative regulation of G-protein coupled receptor protein signaling pathway; unfolded protein response; calcium-mediated signaling; signal transduction; chemotaxis; regulation of retroviral genome replication; induction of positive chemotaxis; negative regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; response to molecule of bacterial origin; receptor internalization; immune response; angiogenesis; cell motility; inflammatory response; cell cycle arrest; embryonic gut development
尺寸1 :
0.1毫克
价格1 :
290美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。