产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
MAPT抗体
目录 :
MBS851873
规格 :
0.1毫克
价格 :
320美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 酶免疫法
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS851873 图像 1
图像 2 :
MyBioSource MBS851873 图像 2
产品信息
目录号 :
MBS851873
产品类型 :
抗体
产品全称 :
MAPT抗体
产品简称 :
[MAPT]
其他名称 :
[microtubule-associated protein tau isoform 1; Microtubule-associated protein tau; microtubule-associated protein tau; microtubule associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau]
产品基因名称 :
[MAPT]
其他基因名称 :
[MAPT; MAPT; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; PPP1R103; MAPTL; MTBT1; TAU; PHF-tau]
克隆性 :
多克隆
宿主 :
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
758
形式 :
Purified by protein A column containing 0.02% NaN3
储存稳定性 :
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)
应用笔记 :
ELISA: 1:10, 000-1:80, 000。 WB: 1:200-1:1, 000
image1头 :
试验数据
image2头 :
试验数据
产品种类 :
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
产品描述 :
Rabbit polyclonal MAPT (1) antibody was raised against a recombinate human MAPT protein 642-754aa(NM_016835).
产品引用 :
(1) Skoglund, L., Ingvast, S., Matsui, T., et al. No evidence of PGRN or MAPT gene dosage alterations in a collection of patients with frontotemporal lobar degeneration.Dement Geriatr Cogn Disord 28 (5), 471-475 (2009).
NCBI GI登录号 :
294862261
NCBI登录号 :
NP_058519.3
NCBI基因登录号 :
NM_016835.4
UniProt数据库登录号 :
P10636
NCBI分子量 :
80,941 Da
NCBI信号通路 :
Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Alzheimers Disease Pathway (672448); Apoptosis Pathway (105648); Apoptotic Cleavage Of Cellular Proteins Pathway (105678); Apoptotic Execution Phase Pathway (105677); BDNF Signaling Pathway (712093); Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway (105679); IL-2 Signaling Pathway (198885); IL-6 Signaling Pathway (198864)
NCBI总结 :
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
尺寸1 :
0.1毫克
价格1 :
320美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。