产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
水闸蛋白4(磷酸化Tyr208)多克隆抗体
目录 :
MBS8520862
规格 :
0.1毫克
价格 :
280美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类
应用 :
酶联免疫吸附测定, 免疫组化, 酶免疫法
更多信息或购买 :
MyBioSource 产品网页
产品信息
目录号 :
MBS8520862
产品类型 :
抗体
产品全称 :
水闸蛋白4(磷酸化Tyr208)多克隆抗体
产品简称 :
[水闸蛋白4]
产品名称同义词 :
[CLDN4; CPER; CPETR1; WBSCR8; Claudin-4; Clostridium perfringens enterotoxin receptor; CPE-R; CPE-receptor; Williams- Beuren syndrome chromosomal region 8 protein]
其他名称 :
[水闸蛋白4;水闸蛋白4;水闸蛋白4;水闸蛋白4;产气荚膜梭菌肠毒素受体]
其他基因名称 :
[CLDN4;CLDN4;CPER;CPE-R;CPETR;CPETR1;WBSCR8;hCPE-R;;CPE受体]
克隆性 :
多克隆
宿主 :
兔
反应物种 :
人类
序列长度 :
209
特异性 :
Phospho-Claudin-4 (Y208) Polyclonal Antibody detects endogenous levels of Claudin-4 protein only when phosphorylated at Y208
纯度 :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
形式 :
液体PBS含50% 甘油, 0.5% BSA和0.02% 叠氮化钠
浓度 :
1毫克/毫升
储存稳定性 :
Store at -20°C / 1 year.
检测过的应用 :
免疫组化(免疫组化), 酶联免疫吸附测定(EIA)
应用笔记 :
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications
其它信息1 :
Immunogen: Synthesized peptide derived from human Claudin-4 around the phosphorylation site of Y208
NCBI GI登录号 :
4502877
NCBI登录号 :
NP_001296.1
NCBI基因登录号 :
NM_001305.4
UniProt数据库登录号 :
O14493
NCBI信号通路 :
Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Junction Organization Pathway (160966); Cell-Cell Communication Pathway (477132); Cell-cell Junction Organization Pathway (119532); Hepatitis C Pathway (173973); Hepatitis C Pathway (173907); Leukocyte Transendothelial Migration Pathway (83083); Leukocyte Transendothelial Migration Pathway (494); Tight Junction Pathway (83071)
NCBI总结 :
The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]
UniProt数据库总结 :
Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
尺寸1 :
0.1毫克
价格1 :
280美元
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。