抗体

Phospho-Occludin (Ser507) Antibody

MBS8528938

0.1毫克

280美元

多克隆

兔

未共轭

人类, 小鼠, 大鼠

抗体

Phospho-Occludin (Ser507) Antibody

[Occludin]

[BLCPMG; FLJ08163; FLJ18079; FLJ77961; FLJ94056; MGC34277; Occludin; OCLN_HUMAN; Tight junction protein occludin]

[occludin isoform a; Occludin; occludin; occludin]

[OCLN]

[OCLN;OCLN;BLCPMG;PTORCH1;PPP1R115]

多克隆

IgG

兔

人类, 小鼠, 大鼠

522

Purified rabbit serum by affinity purification via sequential chromatography on phospho-and non-phospho-peptide affinity columns.

兔IgG在磷酸盐缓冲液, pH值7.4, 150 mM NaCI, 0.02% 叠氮化钠和50% 甘油

Store at -20°C. Stable for 12 months from date of receipt.

免疫印迹(免疫印迹)

WB: 1:500-1:2000

Immunogen: A synthesized peptide derived from human Occludin around the phosphorylation site of Ser507

327478414

NP_001192183.1

NM_001205254.1

Q16625

62kDa

Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Hepatitis C Pathway (173973); Hepatitis C Pathway (173907); Leukocyte Transendothelial Migration Pathway (83083); Leukocyte Transendothelial Migration Pathway (494); Pathogenic Escherichia Coli Infection Pathway (83103); Pathogenic Escherichia Coli Infection Pathway (672459); Pathogenic Escherichia Coli Infection Pathway (516); TGF-beta Receptor Signaling Pathway (138024)

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]

May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions.

0.1毫克

280美元