抗体

基质金属蛋白酶-7抗体

MBS853438

0.1毫克

215美元

多克隆

兔

未共轭

人类, 小鼠, 大鼠

免疫印迹, 酶联免疫吸附测定, 免疫组化, 酶免疫法

抗体

基质金属蛋白酶-7抗体

基质金属蛋白酶-7

PUMP1; PUTATIVE METALLOPROTEINASE I; matrix metalloproteinase 7 (matrilysin; uterine)

matrilysin preproprotein; Matrilysin; matrilysin; matrin; pump-1 protease; uterine matrilysin; uterine metalloproteinase; matrix metalloproteinase-7; matrix metalloproteinase 7 (matrilysin, uterine); matrix metallopeptidase 7 (matrilysin, uterine); Matrin; Matrix metalloproteinase-7; MMP-7; Pump-1 protease; Uterine metalloproteinase

基质金属蛋白酶-7

MMP7;MMP7;基质金属蛋白酶-7;MPSL1;PUMP-1;MPSL1;PUMP1;基质金属蛋白酶-7

MMP7_HUMAN

兔

人类, 小鼠, 大鼠

267

基质金属蛋白酶-7抗体检测内生水平总数基质金属蛋白酶-7蛋白

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

100微克/100微升

Store at -20 degree C for 1 year

免疫印迹(免疫印迹), 免疫组化(免疫组化), 酶联免疫吸附测定(EIA)

WB: 1:500~1:1000, IHC: 1:50~1:100, ELISA: 1:5000

Immunogen: The antiserum was produced against synthesized peptide derived from human MMP-7. Pathway: Translation

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

Lydia E. Wroblewski, J. Cell Sci., Jul 2003; 116: 3017. Andrea Varro, Am J Physiol Gastrointest Liver Physiol, Apr 2007; 292: G1133 - G1140. Wei-Hsuan Yu, Genes & Dev., Feb 2002; 16: 307. Nick Di Girolamo, Invest. Ophthalmol. Vis. Sci., Aug 2001; 42: 1963.

4505219

NP_002414.1

NM_002423.3

P09237

29,677 Da

AGE/RAGE Pathway (698754); Activation Of Matrix Metalloproteinases Pathway (576264); Alpha6-Beta4 Integrin Signaling Pathway (198807); Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway (730306); Collagen Degradation Pathway (730309); Collagen Formation Pathway (645288); Degradation Of The Extracellular Matrix Pathway (576263); Extracellular Matrix Organization Pathway (576262); Matrix Metalloproteinases Pathway (198900); Syndecan-1-mediated Signaling Events Pathway (138046)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

MMP7: Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. Belongs to the peptidase M10A family. Protein type: Protease; EC 3.4.24.23; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 11q22.2. Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region. Molecular Function: zinc ion binding; metalloendopeptidase activity. Biological Process: response to drug; extracellular matrix disassembly; collagen catabolic process; defense response to Gram-positive bacterium; extracellular matrix organization and biogenesis; antibacterial peptide biosynthetic process; proteolysis; defense response to Gram-negative bacterium; antibacterial peptide secretion; regulation of cell proliferation

0.1毫克

215美元