抗体

k-ras Antibody

MBS855216

0.1毫克

290美元

多克隆

兔

未共轭

抗体

k-ras Antibody

k-ras

Homo sapiens Kirsten rat sarcoma viral oncogene homolog (KRAS), transcript variant a, mRNA; GTPase KRas; GTPase KRas; K-Ras 2; c-Ki-ras; oncogene KRAS2; K-ras p21 protein; c-Kirsten-ras protein; PR310 c-K-ras oncogene; transforming protein p21; cellular c-Ki-ras2 proto-oncogene; v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog; Kirsten rat sarcoma viral oncogene homolog; K-Ras 2; Ki-Ras; c-K-ras; c-Ki-rasCleaved into the following chain:GTPase KRas, N-terminally processed

k-ras

KRAS;KRAS;NS;NS3;CFC2;KRAS1;KRAS2;RASK2;KI-RAS;C-K-RAS;K-RAS2A;K-RAS2B;K-RAS4A;K-RAS4B;KRAS2;RASK2

RASK_HUMAN

多克隆

兔

人类

5436

Lyophilized anti-k-ras antibody purified by peptide affinity column containing 2% BSA and 0.02% NaN3

100微克/200微升

免疫印迹(免疫印迹)

Peptide ELISA titer: 1:20,000-1:80,000. Western blot analysis: 1:200-1,000. Optimal dilutions/concentrations should be determined by the end user.

Source Note: Rabbit polyclonal k-ras (1) antibody was raised against a peptide near intermediate residues of human k-ras protein. Reactivity Note: Not yet tested in other species.

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

(1) Estrada,P., Rojas-Atencio,A., Zabala,W., et al. Frequency and clinicopathological associations of K-ras mutations in Venezuelan patients with colo-rectal cancer. Invest Clin 50 (1), 55-63 (2009)

34485724

NP_203524.1

NM_033360

21,425 Da

ARMS-mediated Activation Pathway 106466!!Activation Of RAS In B Cells Pathway 576252!!Acute Myeloid Leukemia Pathway 83117!!Acute Myeloid Leukemia Pathway 529!!Adaptive Immune System Pathway 366160!!Alcoholism Pathway 585563!!Alcoholism Pathway 587116!!Aldosterone-regulated Sodium Reabsorption Pathway 130626!!Aldosterone-regulated Sodium Reabsorption Pathway 130590!!Axon Guidance Pathway 83065

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]

0.1毫克

290美元