产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
CK-18抗体
目录 :
MBS857101
规格 :
0.1毫升
价格 :
290美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
克隆名称 :
19-Jun
反应物种 :
小鼠, 大鼠
应用 :
免疫印迹
更多信息或购买 :
产品信息
目录号 :
MBS857101
产品类型 :
抗体
产品全称 :
CK-18抗体
产品简称 :
CK-18
其他名称 :
keratin, type I cytoskeletal 18; Keratin, type I cytoskeletal 18; keratin, type I cytoskeletal 18; CK-18; Endo B; keratin D; keratin-18; cytokeratin-18; cytokeratin endo B; keratin complex 1, acidic, gene 18; keratin 18; Cytokeratin endo B; Keratin D; Cytokeratin-18; CK-18; Keratin-18; K18
产品基因名称 :
CK-18
其他基因名称 :
Krt18; Krt18; K18; CK18; Krt1-18; Kerd; Krt1-18; Keratin D; CK-18; K18
UniProt数据库进入名 :
K1C18_MOUSE
克隆性 :
多克隆
抗体亚型 :
IgG
克隆 :
19-Jun
宿主 :
兔
反应物种 :
Mouse, Rat
序列长度 :
423
特异性 :
This antibody is produced by immunizing mouse with a synthetic peptide (KLH-coupled) corresponding to near C-terminal residues of CK18.
形式 :
Mouse Monoclonal IgG2a in 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
储存稳定性 :
Store at 4 degree C after thawing. Aliquot store at -20 degree C or -80 degree C. Avoid repeated freeze / thaw cycles.
检测过的应用 :
免疫印迹(免疫印迹)
应用笔记 :
WB: 1:25, 000-50, 000
其他信息2 :
Cellular Localization: Cytoplasm, Nucleus domain
产品种类 :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
产品描述 :
Background: Cytokeratin 18 is an acidic keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas. Cytokeratin 18 exists in combination with Cytokeratin 8, a basic keratin. Hepatocellular carcinomas have been reportedly defined by the use of antibodies that recognize only Cytokeratins 8 and 18.
产品引用 :
1. Singer P.A., Trevor K., Oshima R.G. J. Biol. Chem. 261:538-547(1986). 2. Ichinose Y., Morita T., Zhang F. etc. Gene 70:85-95(1988). 3. Dixon M.J., Robinson V., White A., Ferguson M.W. J. Anat. 183:423-438(1993).
NCBI GI登录号 :
254540068
NCBI登录号 :
NP_034794.2
NCBI基因登录号 :
NM_010664.2
UniProt数据库登录号 :
P05784
NCBI分子量 :
48kDa
NCBI信号通路 :
EGFR1 Signaling Pathway (198278)
UniProt数据库总结 :
K18: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 18 and its filament partner keratin 8 are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Defects are a cause of cryptogenic cirrhosis. Protein type: Nucleolus; Cytoskeletal. Cellular Component: cytoplasm; keratin filament; microtubule organizing center; intermediate filament; nucleus. Molecular Function: protein binding; structural molecule activity. Biological Process: tumor necrosis factor-mediated signaling pathway; intermediate filament cytoskeleton organization and biogenesis; negative regulation of apoptosis; Golgi to plasma membrane CFTR protein transport
尺寸1 :
0.1毫升
价格1 :
290美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。