产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
CD271抗体
目录 :
MBS857122
规格 :
0.1毫升
价格 :
290美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
小鼠, 大鼠
应用 :
免疫印迹
更多信息或购买 :
MyBioSource 产品网页
产品信息
目录号 :
MBS857122
产品类型 :
抗体
产品全称 :
CD271抗体
产品简称 :
CD271
其他名称 :
Tumor necrosis factor receptor superfamily member 16; Tumor necrosis factor receptor superfamily member 16; tumor necrosis factor receptor superfamily member 16; NGF receptor; p75 neurotrophin receptor; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; CD_antigen: CD271
产品基因名称 :
CD271
其他基因名称 :
神经生长因子受体;神经生长因子受体;p75;LNGFR;p75NTR;p75NGFR;Tnfrsf16;Tnfrsf16;神经生长因子受体
UniProt数据库进入名 :
TNR16_MOUSE
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
兔
反应物种 :
Mouse, Rat
序列长度 :
417
特异性 :
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of CD271.
形式 :
液体
储存稳定性 :
Store at 4 degree C after thawing. Aliquot store at -20 degree C or -80 degree C. Avoid repeated freeze / thaw cycles.
检测过的应用 :
免疫印迹(免疫印迹)
应用笔记 :
WB: 1:2, 000~1:5, 000
其他信息2 :
Immunogen: affinity purified. Cellular Localization: Cell membrane
产品种类 :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
产品描述 :
Background: NGFR p75 or CD271 is a 75kD transmembrane glycoprotein consisting of an extracellular domain which contains four cysteine rich domains responsible for ligand binding, a transmembrane domain, and a cytoplasmic domain. NGFR p75 displays paradoxical functions when acting alone or with other receptor proteins. Working in concert with Trk receptors, it recognizes neurotrophins and transmits trophic signals into the cell. NGFR p75 is necessary for regulating neuronal growth, migration, differentiation and cell death during development of the central and peripheral nervous system.
产品引用 :
1. "Low-affinity nerve-growth factor receptor (p75NTR) can serve as a receptor for rabies virus."Tuffereau C., Benejean J., Blondel D., Kieffer B., Flamand A.EMBO J. 17:7250-7259(1998). 2. "Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry."Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J., Faessler R., Mann M.J. Proteome Res. 7:5314-5326(2008)
NCBI GI登录号 :
21264104
NCBI登录号 :
Q9Z0W1.1
UniProt数据库登录号 :
Q9Z0W1
NCBI分子量 :
50kDa
NCBI信号通路 :
Axonal Growth Inhibition (RHOA Activation) Pathway 1000903!!Axonal Growth Stimulation Pathway 1000902!!Cell Death Signalling Via NRAGE, NRIF And NADE Pathway 1000892!!Ceramide Signalling Pathway 1000900!!Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!NADE Modulates Death Signalling Pathway 1000895!!NF-kB Is Activated And Signals Survival Pathway 1000899!!NFG And ProNGF Binds To P75NTR Pathway 1000891!!NRAGE Signals Death Through JNK Pathway 1000893
规格 :
0.1毫升
价格 :
290美元
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。