抗体

I kappa B-alpha (Phospho-Tyr42) Antibody

MBS857349

0.05毫克

225美元

多克隆

兔

未共轭

人类, 小鼠, 大鼠

抗体

I kappa B-alpha (Phospho-Tyr42) Antibody

I kappa B-alpha

IkB-a (Phospho-Tyr42) Antibody

NF-kappa-B inhibitor alpha; NF-kappa-B inhibitor alpha; NF-kappa-B inhibitor alpha; ikB-alpha; IkappaBalpha; I-kappa-B-alpha; nuclear factor of kappa light chain gene enhancer in B-cells; major histocompatibility complex enhancer-binding protein MAD3; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3

NFKBIA; NFKBIA; IKBA; MAD-3; NFKBI; IKBA; MAD3; NFKBI; IkB-alpha; IkappaBalpha

IKBA_HUMAN

多克隆

IgG

兔

人类, 小鼠, 大鼠

317

IkappaB-alpha (phospho-Tyr42) antibody detects endogenous levels of IkappaB-alpha only when phosphorylated at tyrosine 42.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

50微克/50微升

Store at -20 degree C for 1 year

免疫组化(免疫组化)

IHC: 1:50~1:100

Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human IkappaB-alpha around the phosphorylation site of tyrosine 42 (E-E-YP-E-Q). All Sites: Human: Tyr42; Mouse: Tyr42; Rat: Tyr42. Pathway: NF-kappa B, Akt, Cancer/Apoptosis, Insulin/Glucose

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

B©raud C, et al. (1999) Proc Natl Acad Sci U S A 96(2): 429-434. Sundström S, et al. (2005) J Virol 79(4): 2230-2239. Liu L, et al. (1998) Mol Cell Biol 18(7): 4221-4234. Shrivastava A, et al. (1998) J Virol 72(12): 9722-9728.

10092619

NP_065390.1

NM_020529.2

P25963

35,609 Da

AGE/RAGE Pathway 698754!!Activated TLR4 Signalling Pathway 106400!!Activation Of NF-kappaB In B Cells Pathway 576251!!Adaptive Immune System Pathway 366160!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Apoptosis Pathway 198797!!Apoptosis Pathway 83060!!Apoptosis Pathway 470!!Apoptosis Modulation And Signaling Pathway 198822

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]

0.05毫克

225美元