产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
胰岛素B链抗体
目录 :
MBS857374
规格 :
0.1毫升
价格 :
280美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类
应用 :
酶联免疫吸附测定, 酶免疫法
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS857374 图像 1
产品信息
目录号 :
MBS857374
产品类型 :
抗体
产品全称 :
胰岛素B链抗体
产品简称 :
[胰岛素B链]
其他名称 :
[insulin preproprotein; Insulin; insulin; insulin]
产品基因名称 :
[INS]
其他基因名称 :
[INS;INS;IDDM;ILPR;IRDN;IDDM1;IDDM2;MODY10]
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
人类
序列长度 :
110
特异性 :
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to the residues of human ALP.
纯度 :
免疫原亲和纯化
形式 :
1*TBS(pH7.4), 0.5% BSA, 25% 甘油
浓度 :
100微升, 0.53毫克/毫升
储存稳定性 :
Store at +4 degree C after thawing. Aliquot store at-20 degree C or-80 degree C. Avoid repeated freeze/thaw cycles.
检测过的应用 :
酶联免疫吸附测定(EIA)
应用笔记 :
ELISA: 1:500
image1头 :
试验数据
其它信息1 :
Preservative: 0.05% Sodium Azide. Cellular Localization: Secreted. Source Note: This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to human insulin B chain.
其他信息2 :
Positive Control: Recombinannt Human Insulin B Chain
产品描述 :
Insulin is a hormone with extensive effects on both metabolism and several other body systems. It causes most of the body's celis to take up glucose from the blood (including liver, muscle, and fat tissue celis), storing it as glycogen in the liver and muscle, and stops use of fat as an energy source. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to its secretion. Aand B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide.
产品引用 :
1. Ezra E., Blacher R., Udenfriend S.; "Purification and partial sequencing of human placental alkaline phosphatase."; Biochem. Biophys. Res. Commun. 116:1076-1083(1983). 2. Garattini E., Hua J.-C., Pan Y.C.E., Udenfriend S.; "Human liver alkaline phosphatase, purification and partial sequencing: homology with the placental isozyme."; Arch. Biochem. Biophys. 245:331-337(1986).
NCBI GI登录号 :
4557671
NCBI登录号 :
NP_000198.1
NCBI基因登录号 :
NM_000207.2
UniProt数据库登录号 :
P01308
NCBI分子量 :
12kDa
NCBI信号通路 :
AGE/RAGE Pathway (698754); ATF-2 Transcription Factor Network Pathway (138006); Adipogenesis Pathway (198832); Aldosterone-regulated Sodium Reabsorption Pathway (130626); Aldosterone-regulated Sodium Reabsorption Pathway (130590); Amyloids Pathway (366238); Arf6 Trafficking Events Pathway (137954); Cardiac Progenitor Differentiation Pathway (712094); Developmental Biology Pathway (477129); Disease Pathway (530764)
NCBI总结 :
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
UniProt数据库总结 :
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
尺寸1 :
0.1毫升
价格1 :
280美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。