抗体

VEGFR2(Ab-1175)抗体

MBS857447

0.05毫克

180美元

多克隆

兔

未共轭

人类, 小鼠, 大鼠

免疫组化, 免疫细胞化学

抗体

VEGFR2(Ab-1175)抗体

VEGFR2

vascular endothelial growth factor receptor 2; Vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor 2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1; CD_antigen: CD309

VEGFR2

激酶插入区受体;激酶插入区受体;FLK1;CD309;VEGFR;VEGFR2;FLK1;VEGFR2;VEGFR-2;FLK-1;激酶插入区受体

VGFR2_HUMAN

多克隆

IgG

兔

人类, 小鼠, 大鼠

1356

VEGFR2(Ab-1175)抗体检测内生水平总数VEGFR2蛋白

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

50微克/50微升

Store at -20 degree C for 1 year

免疫组化(免疫组化), 免疫荧光(IF)

IHC: 1:50~1:100, IF:1:100~1:200

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human VEGFR2 around the phosphorylation site of tyrosine 1175 (K-D-YP-I-V). Pathway: Receptors, Kinase/Phosphatases

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

Lamalice L, et al. (2004). Oncogene.23(2): 434-445. Takahashi T, et al. (2001). EMBO J.20(11): 2768-2778.

11321597

NP_002244.1

NM_002253.2

P35968

79,634 Da

Angiogenesis Pathway 198772!!Axon Guidance Pathway 105688!!Cardiac Progenitor Differentiation Pathway 712094!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Developmental Biology Pathway 477129!!EPH-Ephrin Signaling Pathway 1016174!!EPHA-mediated Growth Cone Collapse Pathway 1016175!!Endocytosis Pathway 102279!!Endocytosis Pathway 102181

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

0.05毫克

180美元