B-cell surface antigen CD40, Bp50, CD40 antigen, CD40 receptor, CDw40, TNR5; tumor necrosis factor receptor superfamily member 5, TNFRSF5

产品简要

公司名称 :

MyBioSource

产品类型 :

抗体

产品名称 :

B-cell surface antigen CD40, Bp50, CD40 antigen, CD40 receptor, CDw40, TNR5; tumor necrosis factor receptor superfamily member 5, TNFRSF5

MBS859657

规格 :

0.1毫克

价格 :

290美元

克隆性 :

多克隆

宿主 :

兔

共轭标签 :

未共轭

应用 :

免疫印迹, 免疫组化

更多信息或购买 :

MyBioSource 产品网页

产品信息

目录号 :

MBS859657

产品类型 :

抗体

产品全称 :

B-cell surface antigen CD40, Bp50, CD40 antigen, CD40 receptor, CDw40, TNR5; tumor necrosis factor receptor superfamily member 5, TNFRSF5

产品简称 :

CD40

其他名称 :

CD40, partial; CD40; CD40

产品基因名称 :

CD40

UniProt数据库进入名 :

Q09LL4_HUMAN

克隆性 :

多克隆

抗体亚型 :

IgG

宿主 :

兔

反应物种 :

人类, 小鼠

序列长度 :

117

特异性 :

CD40抗体检测内生水平总数CD40蛋白

纯度 :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

形式 :

Rabbit IgG in phosphate buffered saline (without Mg 2+ and Ca 2+ ), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

浓度 :

1毫克/毫升

储存稳定性 :

Store at -20 degree C/1 year

检测过的应用 :

免疫印迹(免疫印迹), 免疫组化(免疫组化)

应用笔记 :

WB: 1:500-1:1000。 IHC: 1:50-1:100。 ELISA: 1 :10000

其它信息1 :

Swiss-Prot No.: P25942. Immunogen: The antiserum was produced against synthesized peptide derived from C-terminal of human CD40.

产品种类 :

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

NCBI GI登录号 :

114053977

NCBI登录号 :

ABI49511.1

NCBI分子量 :

13,158 Da

NCBI总结 :

This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2014]

尺寸1 :

0.1毫克

价格1 :

290美元

更多信息或购买 :

MyBioSource 产品网页

公司信息