产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
CD68
目录 :
MBS9126321
规格 :
0.05毫升
价格 :
200美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS9126321 图像 1
Immunohistochemistry of paraffin-embedded human liver injury using CD68 antibody at dilution of 1:100 (40x lens).
图像 2 :
MyBioSource MBS9126321 图像 2
Immunohistochemistry of paraffin-embedded human esophageal cancer using CD68 antibody at dilution of 1:100 (40x lens).
产品信息
目录号 :
MBS9126321
产品类型 :
抗体
产品全称 :
CD68
产品简称 :
[CD68]
产品名称同义词 :
[GP110;LAMP4;SCARD1]
其他名称 :
[Macrosialin; Macrosialin; macrosialin; CD68 antigen; macrophage antigen CD68; scavenger receptor class D, member 1; CD68 molecule; Gp110; CD_antigen: CD68]
产品基因名称 :
[CD68]
其他基因名称 :
[CD68;CD68;GP110;LAMP4;SCARD1]
UniProt数据库进入名 :
CD68_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
人类
序列长度 :
354
纯度 :
亲和纯化
储存稳定性 :
存放在-20°C。 避免反复冷冻/解冻
检测过的应用 :
免疫印迹(免疫印迹), 免疫组化(免疫组化)
应用笔记 :
WB: 1:500-1:2000。 IHC: 1:50-1:200
image1头 :
免疫组化(免疫组化)
image2头 :
免疫组化(免疫组化)
其它信息1 :
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-319 of human CD58 (NP_001242.2)
其他信息2 :
Buffer: PBS with 0.02% sodium azide, 50% Glycerol, pH 7.3. Calculated MW: 31 kDa/ 34 kDa/37kDa
产品种类 :
多克隆
产品描述 :
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris,promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms
NCBI GI登录号 :
147744552
NCBI登录号 :
P34810.2
UniProt数据库登录号 :
P34810
NCBI信号通路 :
溶体通路(99052);溶体通路(96865)
NCBI总结 :
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
CD68: Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. Belongs to the LAMP family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Cell surface. Chromosomal Location of Human Ortholog: 17p13. Cellular Component: membrane; lysosomal membrane; plasma membrane; integral to membrane; endosome membrane
尺寸1 :
0.05毫升
价格1 :
200美元
尺寸2 :
0.1毫升
价格2 :
275
size3 :
0.2毫升
价格3 :
430
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。