产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
三甲基化组蛋白H3-K56
目录 :
MBS9126783
规格 :
0.05毫升
价格 :
235美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS9126783 图像 1
Western blot analysis of extracts of various cell lines, using TriMethyl-Histone H3-K56 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
产品信息
目录号 :
MBS9126783
产品类型 :
抗体
产品全称 :
三甲基化组蛋白H3-K56
产品简称 :
[H3-K56]
其他名称 :
[histone H3-K56 acetyltransferase, RTT109, partial; Histone H3.1; histone H3.1; histone H3/j; histone 1, H3j; H3 histone family, member J; histone cluster 1, H3j; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l]
产品基因名称 :
[H3K56me3]
其他基因名称 :
[HIST1H3J;HIST1H3A;H3/j;H3FJ;H3FA]
UniProt数据库进入名 :
H31_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
Human, Mouse, Rat, Other (Wide Range)
序列长度 :
146
纯度 :
亲和纯化
储存稳定性 :
Store at -20 Degree C (regular) or -80 Degree C (long term). Avoid freeze / thaw cycles.
检测过的应用 :
免疫印迹(免疫印迹), 免疫组化(免疫组化), 免疫荧光(IF), 免疫沉淀(免疫沉淀), CHIP, CHIPseq
应用笔记 :
免疫印迹1:500-1:2000。 免疫组化1:50-1:200。 IF 1:50 - 1:200。 免疫沉淀1:50-1:200。 ChIP 1:20 - 1:100。 CHIPseq 1:20 - 1:100
image1头 :
免疫印迹(免疫印迹)
其它信息1 :
Species: Human. Route: Synthetic Peptide. Immunogen : A synthetic peptide of human HIST3H3. Gene ID : 8290. Swiss Prot: Q16695. Synonyms: H3t; H3.4; H3/g; H3FT;
其他信息2 :
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
产品种类 :
甲基化
产品描述 :
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
NCBI GI登录号 :
743667947
NCBI登录号 :
KID94952.1
NCBI分子量 :
16kDa
NCBI信号通路 :
Alcoholism Pathway (585563); Alcoholism Pathway (587116); Amyloids Pathway (366238); Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); Cellular Senescence Pathway (905991); Cellular Responses To Stress Pathway (645258); Chromatin Modifying Enzymes Pathway (1127682); Chromatin Organization Pathway (1127681); Condensation Of Prophase Chromosomes Pathway (1127547)
NCBI总结 :
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
H3: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Belongs to the histone H3 family. Protein type: DNA-binding. Chromosomal Location of Human Ortholog: 6p22.2. Cellular Component: nucleoplasm; nuclear chromosome; protein complex; membrane; extracellular region; nucleosome; nucleus. Molecular Function: protein binding; DNA binding; histone binding; protein heterodimerization activity. Biological Process: chromatin silencing at rDNA; nucleosome assembly; establishment and/or maintenance of chromatin architecture; negative regulation of gene expression, epigenetic; protein heterotetramerization; gene expression; blood coagulation; DNA replication-dependent nucleosome assembly; regulation of gene expression, epigenetic; DNA methylation on cytosine
尺寸1 :
0.05毫升
价格1 :
235美元
尺寸2 :
0.1毫升
价格2 :
350
size3 :
0.2毫升
价格3 :
525
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。