产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
Human Pancreatic secretory trypsin inhibitor, SPINK1 ELISA Kit
目录 :
MBS913572
规格 :
48-Strip-Wells
价格 :
510美元
更多信息或购买 :
产品信息
目录号 :
MBS913572
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
Human Pancreatic secretory trypsin inhibitor, SPINK1 ELISA Kit
产品简称 :
serine peptidase inhibitor, Kazal type 1
产品名称同义词 :
Human Pancreatic secretory trypsin inhibitor (SPINK1) ELISA kit; PCTT; PSTI; Spink3; TATI; pancreatic secretory trypsin inhibitor; serine protease inhibitor; Kazal type 1; tumor-associated trypsin inhibitor; serine peptidase inhibitor; Kazal type 1
其他名称 :
pancreatic secretory trypsin inhibitor; Pancreatic secretory trypsin inhibitor; pancreatic secretory trypsin inhibitor; tumor-associated trypsin inhibitor; serine protease inhibitor, Kazal type 1; serine peptidase inhibitor, Kazal type 1; Serine protease inhibitor Kazal-type 1; Tumor-associated trypsin inhibitor; TATI
产品基因名称 :
SPINK1
其他基因名称 :
SPINK1;SPINK1;TCP;PCTT;PSTI;TATI;Spink3;PSTI;TATI
UniProt数据库进入名 :
ISK1_HUMAN
反应物种 :
人类
序列长度 :
79
特异性 :
This assay has high sensitivity and excellent specificity for detection of Human SPINK1. No significant cross-reactivity or interference between Human SPINK1 and analogues was observed.
储存稳定性 :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
其它信息1 :
Samples: Serum, plasma, urine, cell culture supernates. Assay Type: Sandwich. Detection Range: 3.12 ng/ml-200 ng/ml. Sensitivity: 0.78 ng/ml
其他信息2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul
产品描述 :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for SPINK1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any SPINK1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SPINK1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SPINK1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
NCBI GI登录号 :
45505132
NCBI登录号 :
NP_003113.2
NCBI基因登录号 :
NM_003122.4
UniProt数据库登录号 :
P00995
NCBI分子量 :
8,507 Da
NCBI总结 :
The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008]
UniProt数据库总结 :
SPINK1: This is a trypsin inhibitor, its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Defects in SPINK1 are the cause of susceptibility to tropical calcific pancreatitis (TCP). TCP is an idiopathic, juvenile, nonalcoholic form of chronic pancreatitis widely prevalent in several tropical countries. It can be associated with fibrocalculous pancreatic diabetes (FCPD) depending on both environmental and genetic factors. TCP differs from alcoholic pancreatitis by a much younger age of onset, pancreatic calcification, a high incidence of insulin dependent but ketosis resistant diabetes mellitus, and an exceptionally high incidence of pancreatic cancer. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 5q32. Cellular Component: extracellular space. Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; endopeptidase inhibitor activity. Biological Process: negative regulation of peptidyl-tyrosine phosphorylation; regulation of acrosome reaction. Disease: Tropical Calcific Pancreatitis; Pancreatitis, Hereditary
尺寸1 :
48-Strip-Wells
价格1 :
510美元
尺寸2 :
96-Strip-Wells
价格2 :
725
size3 :
5x96-Strip-Wells
价格3 :
2565
size4 :
10x96-Strip-Wells
price4 :
4800
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。