抗体

ACTA1/阿尔法肌动蛋白抗体(C末端)

MBS9200947

0.08毫升

165美元

多克隆

兔

未共轭

人类, 小鼠, 大鼠, 鸡, 牛

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪, 流式细胞仪, 免疫组化-石蜡切片

抗体

ACTA1/阿尔法肌动蛋白抗体(C末端)

[ACTA1/阿尔法肌动蛋白]

[ACTA1/a肌动蛋白抗体(C末端);肌动蛋白;甲骨骼肌;阿尔法肌动蛋白;ACTA1;ACTA]

[肌动蛋白, 甲骨骼肌;肌动蛋白, 甲骨骼肌;肌动蛋白, 甲骨骼肌;肌动蛋白, 甲1, 骨骼肌;阿尔法肌动蛋白]

[ACTA1]

[ACTA1;ACTA1;ACTA;ASMA;CFTD;MPFD;NEM1;NEM2;NEM3;CFTD1;CFTDM;ACTA]

ACTS_HUMAN

多克隆

兔IgE

兔

Humam; (Predicted Reactivity: Xenopus, Bovine, Chicken, Mouse, Rabbit, Rat, Pig)

[346-375]

377

This ACTA1/Alpha-actin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from the C-terminal region of human ACTA1/Alpha-actin.

肽亲和纯化兔多克隆抗体(多克隆抗体)

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

免疫组化(免疫组化-P), 免疫荧光(IF), 免疫印迹(免疫印迹), 流式细胞仪(FC/流式细胞仪), 酶联免疫吸附测定

WB~~1:1000。 免疫组化-P~~1:10~50。 IF~~1:10~50。 FC: 1:10~50

免疫印迹(免疫印迹)

免疫组化(免疫组化)

免疫荧光(IF)

流式细胞仪(FC/流式细胞仪)

ACTA1/alpha-actin Antibody (C-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Cellular Location: Cytoplasm, cytoskeleton

Crown Antibodies; Cancer; Cell Biology

The product encoded by this gene belongs to the actin. family of proteins, which are highly conserved proteins that play a. role in cell motility, structure and integrity. Alpha, beta and. gamma actin isoforms have been identified, with alpha actins being. a major constituent of the contractile apparatus, while beta and. gamma actins are involved in the regulation of cell motility. This. actin is an alpha actin that is found in skeletal muscle. Mutations. in this gene cause nemaline myopathy type 3, congenital myopathy. with excess of thin myofilaments, congenital myopathy with cores,. and congenital myopathy with fiber-type disproportion, diseases. that lead to muscle fiber defects.

Kim, E.Y., et al. Am. J. Physiol. Renal Physiol. 299 (3), F594-F604 (2010) :. Haigh, S.E., et al. Neuromuscul. Disord. 20(6):363-374(2010). Yu, G., et al. J Clin Neurosci 17(6):766-769(2010). Yu, C.H., et al. PLoS ONE 5 (7), E11878 (2010) :. Licastro, F., et al. Curr. Pharm. Des. 16(7):783-788(2010)

4501881

NP_001091.1

NM_001100.3

P68133

42051

Peptidoglycan Biosynthesis I (meso-diaminopimelate Containing) Pathway (58); Peptidoglycan Biosynthesis I (meso-diaminopimelate Containing) Pathway (58); Peptidoglycan Biosynthesis I (meso-diaminopimelate Containing) Pathway (58); Peptidoglycan Biosynthesis I (meso-diaminopimelate Containing) Pathway (58); Peptidoglycan Biosynthesis I (meso-diaminopimelate Containing) Pathway (58); Peptidoglycan Biosynthesis I (meso-diaminopimelate Containing) Pathway (58)

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008]

ACTA1: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Interacts with TTID. Interacts (via its C-terminus) with USP25; the interaction occurs for all USP25 isoforms but is strongest for isoform USP25m in muscle differentiating cells. Belongs to the actin family. Protein type: Cell development/differentiation; Cytoskeletal; Contractile; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 1q42.13. Cellular Component: extracellular space; sarcomere; stress fiber; actin filament; cytosol; striated muscle thin filament; actin cytoskeleton. Molecular Function: protein binding; myosin binding; structural constituent of cytoskeleton; ADP binding; ATP binding. Biological Process: skeletal muscle fiber adaptation; muscle contraction; muscle thin filament assembly; response to mechanical stimulus; response to steroid hormone stimulus; response to lithium ion; response to extracellular stimulus; skeletal muscle fiber development; cell growth; muscle filament sliding. Disease: Nemaline Myopathy 3; Myopathy, Congenital, With Fiber-type Disproportion

0.08毫升

165美元

0.4毫升

370