产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
PRDX1 Antibody (Center)
目录 :
MBS9203640
规格 :
0.08毫升
价格 :
165美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 流式细胞仪, 流式细胞仪, 酶免疫法, 免疫组化-石蜡切片
更多信息或购买 :
图像
图像 1 :
Western blot analysis of PRDX1 Antibody (Center) in CEM cell line lysates (35ug/lane). PRDX1 (arrow) was detected using the purified Pab.
图像 2 :
Western blot analysis of PRDX1 (arrow) using rabbit polyclonal PRDX1 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PRDX1 gene (Lane 2).
图像 3 :
PRDX1 Antibody (Center) flow cytometric analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
产品信息
目录号 :
MBS9203640
产品类型 :
抗体
产品全称 :
PRDX1 Antibody (Center)
产品简称 :
[PRDX1]
产品名称同义词 :
[Peroxiredoxin-1; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2; PRDX1; PAGA; PAGB; TDPX2]
其他名称 :
[peroxiredoxin-1; Peroxiredoxin-1; peroxiredoxin-1; peroxiredoxin 1; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2]
产品基因名称 :
[PRDX1]
其他基因名称 :
[PRDX1;PRDX1;PAG;PAGA;PAGB;PRX1;PRXI;MSP23;NKEFA;TDPX2;NKEF-A;PAGA;PAGB;TDPX2;NKEF-A;PAG]
UniProt数据库进入名 :
PRDX1_HUMAN
克隆性 :
多克隆
抗体亚型 :
兔IgE
宿主 :
兔
反应物种 :
Human (Predicted Reactivity: Hamster, Rat)
序列位置 :
[88-116]
特异性 :
This PRDX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the Central region of human PRDX1.
纯度 :
纯化兔多克隆抗体(多克隆抗体)
形式 :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
储存稳定性 :
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
检测过的应用 :
免疫印迹(免疫印迹), 酶联免疫吸附测定(EIA), 流式细胞仪(FC/流式细胞仪), 免疫组化石蜡(免疫组化-P)
应用笔记 :
WB~~1:1000。 FC~~1:10~50。 免疫组化-P~~1:50~100
image1头 :
免疫印迹(免疫印迹)
image2头 :
免疫印迹(免疫印迹)
image3头 :
流式细胞仪(FC/流式细胞仪)
image4头 :
免疫组化(免疫组化)
image4描述 :
PRDX1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PRDX1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
其它信息1 :
Function: Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).
其他信息2 :
Cellular Location: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
产品种类 :
Cancer; Cardiovascular; Cell Biology; Metabolism; Signal Transduction
产品描述 :
PRDX1 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. This protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression.
产品引用 :
Song,I.S., et.al., Carcinogenesis 30 (7), 1106-1114 (2009)
NCBI GI登录号 :
320461711
NCBI登录号 :
NP_001189360.1
NCBI基因登录号 :
NM_001202431.1
UniProt数据库登录号 :
Q06830
NCBI分子量 :
22110
NCBI总结 :
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011]
UniProt数据库总结 :
PRDX1: a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). May have a proliferative effect and play a role in cancer development or progression. Protein type: Oxidoreductase; Nuclear receptor co-regulator; EC 1.11.1.15. Chromosomal Location of Human Ortholog: 1p34.1. Cellular Component: peroxisomal matrix; extracellular space; mitochondrial matrix; cytoplasm; nucleolus; melanosome; cytosol; nucleus. Molecular Function: protein binding; peroxidase activity; protein homodimerization activity; thioredoxin peroxidase activity; heme binding. Biological Process: erythrocyte homeostasis; retinal homeostasis; cell proliferation; regulation of stress-activated MAPK cascade; response to reactive oxygen species; removal of superoxide radicals; natural killer cell mediated cytotoxicity; hydrogen peroxide catabolic process; skeletal development; regulation of NF-kappaB import into nucleus
尺寸1 :
0.08毫升
价格1 :
165美元
尺寸2 :
0.4毫升
价格2 :
370
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。
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