抗体

LIF Antibody (Center)

MBS9205709

0.08毫升

150美元

多克隆

兔

未共轭

免疫印迹, 酶联免疫吸附测定, 免疫组化, 流式细胞仪, 流式细胞仪, 酶免疫法

抗体

LIF Antibody (Center)

[LIF]

[Leukemia inhibitory factor; LIF; Differentiation-stimulating factor; D factor; Melanoma-derived LPL inhibitor; MLPLI; Emfilermin; LIF; HILDA]

[leukemia inhibitory factor isoform 2; Leukemia inhibitory factor; leukemia inhibitory factor; leukemia inhibitory factor; Differentiation-stimulating factor; D factor; Melanoma-derived LPL inhibitor; MLPLI; INN: Emfilermin]

[LIF]

[LIF; LIF; CDF; DIA; HILDA; MLPLI; HILDA; LIF; D factor; MLPLI]

LIF_HUMAN

多克隆

兔IgE

兔

人类

[72-101]

88

This LIF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human LIF.

肽亲和纯化兔多克隆抗体(多克隆抗体)

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Vial Concentration: 0.5

Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

免疫印迹(免疫印迹), 酶联免疫吸附测定(EIA), 免疫组化(免疫组化), 流式细胞仪(FC/流式细胞仪)

WB~~1:1000

免疫印迹(免疫印迹)

免疫印迹

Antigen Type: Synthetic Peptide

Antigen Source: HUMAN

Cancer; Cell Biology; Immunology; Neuroscience; Signal Transduction

LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface.

Novotny,Z., et.al., Folia Biol. (Praha) 55 (3), 92-97 (2009)

380418324

NP_001244064.1

NM_001257135.1

P15018

22008

The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]

LIF: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. Belongs to the LIF/OSM family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 22q12.2. Cellular Component: extracellular space; cytoplasm. Molecular Function: growth factor activity; leukemia inhibitory factor receptor binding; cytokine activity; receptor binding. Biological Process: transcription from RNA polymerase II promoter; leukemia inhibitory factor signaling pathway; multicellular organismal development; negative regulation of hormone secretion; stem cell maintenance; tyrosine phosphorylation of Stat3 protein; decidualization; positive regulation of peptidyl-serine phosphorylation; positive regulation of tyrosine phosphorylation of Stat3 protein; negative regulation of cell proliferation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of tyrosine phosphorylation of Stat1 protein; positive regulation of MAPKKK cascade; negative regulation of meiosis; positive regulation of cell proliferation; neuron development; immune response; positive regulation of transcription from RNA polymerase II promoter; blood vessel remodeling; positive regulation of macrophage differentiation; muscle morphogenesis; alveolus development; embryo implantation; positive regulation of peptidyl-serine phosphorylation of STAT protein; positive regulation of astrocyte differentiation

0.08毫升

150美元