产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
MLXIPL抗体(C末端)
目录 :
MBS9208417
规格 :
0.08毫升
价格 :
165美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 酶免疫法
更多信息或购买 :
图像
图像 1 :
All lanes : Anti-MLXIPL Antibody (C-term) at 1:2000 dilution . Lane 1: Neuro-2a whole cell lysate . Lane 2: SW620 whole cell lysate Lysates/proteins at 20 ?g per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 93 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
图像 2 :
All lanes : Anti-MLXIPL Antibody (C-term) at 1:2000 dilution . Lane 1: K562 whole cell lysate . Lane 2: NCI-H1299 whole cell lysate . Lane 3: Neuro-2a whole cell lysate . Lane 4: SW620 whole cell lysate Lysates/proteins at 20 ?g per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 93 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
图像 3 :
MLXIPL Antibody (C-term) (Cat. #MBS9208417) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the MLXIPL antibody detected the MLXIPL protein (arrow).
产品信息
目录号 :
MBS9208417
产品类型 :
抗体
产品全称 :
MLXIPL抗体(C末端)
产品简称 :
[MLXIPL]
产品名称同义词 :
[Carbohydrate-responsive element-binding protein; ChREBP; Class D basic helix-loop-helix protein 14; bHLHd14; MLX interactor; MLX-interacting protein-like; WS basic-helix-loop-helix leucine zipper protein; WS-bHLH; Williams-Beuren syndrome chromosomal region 14 protein; MLXIPL; BHLHD14; MIO; WBSCR14]
其他名称 :
[carbohydrate-responsive element-binding protein isoform alpha; Carbohydrate-responsive element-binding protein; carbohydrate-responsive element-binding protein; MLX interacting protein-like; Class D basic helix-loop-helix protein 14; bHLHd14; MLX interactor; MLX-interacting protein-like; WS basic-helix-loop-helix leucine zipper protein; WS-bHLH; Williams-Beuren syndrome chromosomal region 14 protein]
产品基因名称 :
[MLXIPL]
其他基因名称 :
[MLXIPL;MLXIPL;MIO;CHREBP;MONDOB;WBSCR14;WS-bHLH;bHLHd14;BHLHD14;MIO;WBSCR14;ChREBP;bHLHd14;WS-bHLH]
UniProt数据库进入名 :
MLXPL_HUMAN
克隆性 :
多克隆
抗体亚型 :
兔IgE
宿主 :
兔
反应物种 :
人类, 小鼠
序列位置 :
[624-653]
序列长度 :
722
特异性 :
This MLXIPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 624-653 amino acids from the C-terminal region of human MLXIPL.
纯度 :
肽亲和纯化兔多克隆抗体(多克隆抗体)
形式 :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
浓度 :
Vial Concentration: 0.32
储存稳定性 :
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
检测过的应用 :
免疫印迹(免疫印迹), 酶联免疫吸附测定(EIA), 免疫组化(免疫组化)
应用笔记 :
WB~~1:1000
image1头 :
免疫印迹(免疫印迹)
image2头 :
免疫印迹
image3头 :
免疫印迹
image4头 :
免疫组化
image4描述 :
MLXIPL Antibody (C-term) (Cat. #MBS9208417)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MLXIPL Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
其它信息1 :
Antigen Type: Synthetic Peptide
其他信息2 :
Antigen Source: HUMAN. Function: Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3' (By similarity). Cellular Location: Nucleus. Tissue Location: Expressed in liver, heart, kidney, cerebellum and intestinal tissues
产品种类 :
Cancer; Cardiovascular; Metabolism
产品描述 :
This gene encodes a basic helix-loop-helix leucine zipper. transcription factor of the Myc/Max/Mad superfamily. This protein. forms a heterodimeric complex and binds and activates, in a. glucose-dependent manner, carbohydrate response element (ChoRE). motifs in the promoters of triglyceride synthesis genes. The gene. is deleted in Williams-Beuren syndrome, a multisystem developmental. disorder caused by the deletion of contiguous genes at chromosome. 7q11.23.
产品引用 :
Hu, M., et al. Pharmacogenet. Genomics 20(10):634-637(2010). Johansen, C.T., et al. Nat. Genet. 42(8):684-687(2010). Keebler, M.E., et al. Circ Cardiovasc Genet 3(4):358-364(2010). Chidambaram, M., et al. Metab. Clin. Exp. (2010) In press :. Reynolds, C.A., et al. Hum. Mol. Genet. 19(10):2068-2078(2010)
NCBI GI登录号 :
14602433
NCBI登录号 :
NP_116569.1
NCBI基因登录号 :
NM_032951.2
UniProt数据库登录号 :
Q9NP71
NCBI分子量 :
93073
NCBI总结 :
This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
ChREBP: Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5 -CACGTG-3 . Binds DNA as a heterodimer with TCFL4/MLX. Expressed in liver, heart, kidney, cerebellum and intestinal tissues. 6 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription factor. Chromosomal Location of Human Ortholog: 7q11.23. Cellular Component: nucleoplasm; transcription factor complex; cytoplasm; cytosol; nucleus. Molecular Function: protein homodimerization activity; DNA binding; protein heterodimerization activity; transcription factor binding; transcription factor activity. Biological Process: positive regulation of fatty acid biosynthetic process; anatomical structure morphogenesis; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; negative regulation of peptidyl-serine phosphorylation; positive regulation of cellular metabolic process; positive regulation of lipid biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; glucose homeostasis; glucose mediated signaling; regulation of transcription from RNA polymerase II promoter; regulation of fatty acid biosynthetic process; regulation of transcription, DNA-dependent; fatty acid homeostasis; positive regulation of cell proliferation; positive regulation of glycolysis; energy reserve metabolic process; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent. Disease: Williams-beuren Syndrome
尺寸1 :
0.08毫升
价格1 :
165美元
尺寸2 :
0.4毫升
价格2 :
370
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。