抗体

ADCY9抗体(C末端)

MBS9210037

0.08毫升

155美元

多克隆

兔

未共轭

人类, 小鼠

免疫印迹, 酶联免疫吸附测定, 酶免疫法

抗体

ADCY9抗体(C末端)

ADCY9

Adenylate cyclase type 9; ATP pyrophosphate-lyase 9; Adenylate cyclase type IX; Adenylyl cyclase 9; ADCY9; KIAA0520

adenylate cyclase type 9; Adenylate cyclase type 9; adenylate cyclase type 9; adenylate cyclase 9; ATP pyrophosphate-lyase 9; Adenylate cyclase type IX; Adenylyl cyclase 9

ADCY9

ADCY9;ADCY9;AC9;KIAA0520

ADCY9_HUMAN

多克隆

兔IgE

兔

人类, 小鼠

1295-1323

1353

This ADCY9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1295-1323 amino acids from the C-terminal region of human ADCY9.

肽亲和纯化兔多克隆抗体(多克隆抗体)

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Vial Concentration: 0.5

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

免疫印迹(免疫印迹), 酶联免疫吸附测定(EIA)

WB~~1:1000. Cellular Location: Membrance; Multi-pass membrane protein. Tissue Location: Expressed in multiple cells of the lung, with expression highest in airway smooth muscle distributed adenlyl cyclase, and it is stimulate by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin.

Antigen Type: Synthetic Peptide

Antigen Source: HUMAN

Cancer; Metabolism; Signal Transduction

Adenylate cyclase is a membrane bound enzyme that. catalyses the formation of cyclic AMP from ATP. It is regulated by. a family of G protein-coupled receptors, protein kinases, and. calcium. The type 9 adenylyl cyclase is a widely distributed. adenylyl cyclase, and it is stimulated by beta-adrenergic receptor. activation but is insensitive to forskolin, calcium, and. somatostatin. Function: May play a fundamental role in situations where fine interphlay between intracellular calcium and cAMP determines the cellular function. May be a phyciologically relevant docking site for calcineurin (By similarity).

Wojcik, C., et al. Am. J. Med. Genet. A 152A (2), 479-483 (2010) :. Olsen, J.V., et al. Cell 127(3):635-648(2006). Tantisira, K.G., et al. Hum. Mol. Genet. 14(12):1671-1677(2005). Cumbay, M.G., et al. J. Pharmacol. Exp. Ther. 310(1):108-115(2004). Small, K.M., et al. Pharmacogenetics 13(9):535-541(2003)

50959205

NP_001107.2

NM_001116.3

O60503

150701

Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115)

Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. [provided by RefSeq, Jul 2008]

ADCY9: May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Protein type: Transporter, aquaporin family; Adenylyl cyclase; Nucleotide Metabolism - purine; Lyase; Transporter; EC 4.6.1.1; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: metal ion binding; ATP binding; adenylate cyclase activity. Biological Process: epidermal growth factor receptor signaling pathway; synaptic transmission; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; phospholipase C activation; water transport; activation of protein kinase A; energy reserve metabolic process; renal water homeostasis; innate immune response; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; signal transduction; G-protein signaling, adenylate cyclase activating pathway; transmembrane transport

0.08毫升

155美元

0.4毫升

340