产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
FABP4抗体(Y20)
目录 :
MBS9210294
规格 :
0.08毫升
价格 :
165美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS9210294 图像 1
All lanes : Anti-FABP4 Antibody (Y20) at 1:2000-1:8000 dilution. Lane 1: Human skeletal muslce lysate . Lane 2: Human lung lysate. Lane 3: Human heart lysate. Lane 4: Rat heart lysate . Lane 5: 3T3/L1 whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 15 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
产品信息
目录号 :
MBS9210294
产品类型 :
抗体
产品全称 :
FABP4抗体(Y20)
产品简称 :
[FABP4]
产品名称同义词 :
[脂肪酸结合蛋白;脂肪细胞 ;脂肪细胞 血脂结合蛋白;ALBP;脂肪细胞 类型脂肪酸结合蛋白;A-FABP;AFABP;脂肪酸结合蛋白4;FABP4]
其他名称 :
[脂肪酸结合蛋白, 脂肪细胞 ;脂肪酸结合蛋白, 脂肪细胞 ;脂肪酸结合蛋白, 脂肪细胞 ;脂肪酸结合蛋白4, 脂肪细胞 ;脂肪细胞 血脂结合蛋白;ALBP;脂肪细胞 类型脂肪酸结合蛋白;A-FABP;AFABP;脂肪酸结合蛋白4]
产品基因名称 :
[FABP4]
其他基因名称 :
[FABP4;FABP4;aP2;ALBP;AFABP;A-FABP;HEL-S-104;ALBP;A-FABP;AFABP]
UniProt数据库进入名 :
FABP4_HUMAN
克隆性 :
多克隆
抗体亚型 :
兔IgE
宿主 :
反应物种 :
Reactivity: Human, Mouse,Rat. Predicted: Rat, Pig, Bovine
序列位置 :
[1-30]
序列长度 :
132
特异性 :
This FABP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human FABP4.
纯度 :
肽亲和纯化兔多克隆抗体(多克隆抗体)
形式 :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
浓度 :
Vial Concentration: 0.47
储存稳定性 :
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
检测过的应用 :
免疫印迹(免疫印迹)
应用笔记 :
WB~~1:2000-1:8000
image1头 :
试验数据
其它信息1 :
Antigen Type: Synthetic Peptide
其他信息2 :
Antigen Source: HUMAN. Function: Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity). Cellular Location: Cytoplasm. Nucleus. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export (By similarity)
产品种类 :
Cancer; Cardiovascular; Metabolism; Signal Transduction
产品描述 :
FABP4 is a fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism.
产品引用 :
Cabre,A., J. Lipid Res. 49 (8), 1746-1751 (2008). Fasshauer,M., Am. J. Hypertens. 21 (5), 582-586 (2008). Cabre,A., Clin. Chem. 54 (1), 181-187 (2008)
NCBI GI登录号 :
4557579
NCBI登录号 :
NP_001433.1
NCBI基因登录号 :
NM_001442.2
UniProt数据库登录号 :
P15090
NCBI分子量 :
14719
NCBI总结 :
FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
FABP4: a lipid transport protein that is the predominant fatty acid binding protein found in adipocytes. Also expressed in macrophages. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. Homodimer. Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior. Interacts with PPARG. Monomer. FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes. Mice deficient in both FABP4 and ApoE show protection against atherosclerosis when compared with mice deficient only in ApoE. Mice carrying a FABP4 genetic variant exhibit both reduced FABP4 expression and a reduced potential for developing type 2 diabetes and coronary heart disease. A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders. Belongs to the calycin superfamily,fatty-acid binding protein (FABP) family. Protein type: Lipid-binding. Chromosomal Location of Human Ortholog: 8q21. Cellular Component: cytoplasm; lipid particle; nucleus. Molecular Function: transporter activity; fatty acid binding. Biological Process: cholesterol homeostasis; transport; triacylglycerol catabolic process; white fat cell differentiation; brown fat cell differentiation; cytokine production; negative regulation of protein kinase activity; negative regulation of transcription, DNA-dependent; positive regulation of inflammatory response
尺寸1 :
0.08毫升
价格1 :
165美元
尺寸2 :
0.4毫升
价格2 :
370
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。