产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
小鼠酪氨酸羟化酶, TH酶联免疫吸附试剂盒
目录 :
MBS926829
规格 :
48-Strip-Wells
价格 :
565美元
更多信息或购买 :
产品信息
目录号 :
MBS926829
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
小鼠酪氨酸羟化酶, TH酶联免疫吸附试剂盒
产品简称 :
酪氨酸羟化酶(TH)
产品名称同义词 :
小鼠酪氨酸羟化酶(TH)酶联免疫吸附试剂盒;DYT14;DYT5b;TYH;张力障碍14;酪氨酸3单加氧酶;酪氨酸羟化酶(TH)
其他名称 :
tyrosine 3-monooxygenase; Tyrosine 3-monooxygenase; tyrosine 3-monooxygenase; tyrosine 3-hydroxylase; tyrosine hydroxylase; Tyrosine 3-hydroxylase; TH
产品基因名称 :
TH
其他基因名称 :
Th; Th; TH
UniProt数据库进入名 :
TY3H_MOUSE
反应物种 :
小鼠
序列长度 :
498
特异性 :
This assay has high sensitivity and excellent specificity for detection of Mouse TH. No significant cross-reactivity or interference between Mouse TH and analogues was observed.
储存稳定性 :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
其它信息1 :
Samples: Serum, plasma, tissue homogenates and cell culture supernates. Assay Type: Sandwich. Detection Range: 0.625 ng/ml-40 ng/ml. Sensitivity: 0.156 ng/ml
其他信息2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Biosynthesis/Metabolism. Protein Biological Process 2: biogenic amine biosynthesis and metabolism. Protein Biological Process 3: Catecholamine biosynthesis
产品描述 :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for TH has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TH present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TH is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TH bound in the initial step. The color development is stopped and the intensity of the color is measured.
NCBI GI登录号 :
6678337
NCBI登录号 :
NP_033403.1
NCBI基因登录号 :
NM_009377.1
UniProt数据库登录号 :
P24529
NCBI分子量 :
55,993 Da
NCBI信号通路 :
Alcoholism Pathway (585577); Alcoholism Pathway (587116); Amine-derived Hormones Pathway (574876); Amphetamine Addiction Pathway (547634); Amphetamine Addiction Pathway (550546); Biogenic Amine Synthesis Pathway (198386); Catecholamine Biosynthesis Pathway (574877); Catecholamine Biosynthesis, Tyrosine = Dopamine = Noradrenaline = Adrenaline Pathway (421757); Catecholamine Biosynthesis, Tyrosine = Dopamine = Noradrenaline = Adrenaline Pathway (468235); Cocaine Addiction Pathway (546267)
UniProt数据库总结 :
TH: an enzyme involved in the conversion of phenylalanine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Four splice variant isoforms have been described. Protein type: Amino Acid Metabolism - tyrosine; Endoplasmic reticulum; Vesicle; EC 1.14.16.2; Oxidoreductase; Mitochondrial. Cellular Component: internal side of plasma membrane; neuron projection; cytoplasmic vesicle membrane; smooth endoplasmic reticulum; mitochondrion; dendrite; melanosome membrane; terminal button; perikaryon; cytosol; synaptic vesicle; cell soma; axon; cytoplasm; cytoplasmic vesicle; nucleus. Molecular Function: protein domain specific binding; ferric iron binding; metal ion binding; ferrous iron binding; oxidoreductase activity; oxygen binding; tyrosine 3-monooxygenase activity; amino acid binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen; enzyme binding; iron ion binding; dopamine binding; monooxygenase activity. Biological Process: synaptic transmission, dopaminergic; eating behavior; heart development; mating behavior; locomotory behavior; learning; dopamine biosynthetic process; memory; synaptic vesicle amine transport; regulation of heart contraction; norepinephrine biosynthetic process; dopamine biosynthetic process from tyrosine; organ morphogenesis; eye photoreceptor cell development; response to ethanol; catecholamine biosynthetic process; visual perception; aromatic amino acid family metabolic process; response to hypoxia; embryonic camera-type eye morphogenesis; epinephrine biosynthetic process; neurotransmitter biosynthetic process
尺寸1 :
48-Strip-Wells
价格1 :
565美元
尺寸2 :
96-Strip-Wells
价格2 :
810
size3 :
5x96-Strip-Wells
价格3 :
2750
size4 :
10x96-Strip-Wells
price4 :
5150
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。