产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
人类内皮素1, ET-1酶联免疫吸附试剂盒
目录 :
MBS9302251
规格 :
48-Strip-Wells
价格 :
435美元
更多信息或购买 :
产品信息
目录号 :
MBS9302251
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
人类内皮素1, ET-1酶联免疫吸附试剂盒
产品简称 :
内皮素1, ET-1
其他名称 :
内皮素1;内皮素1;内皮素1;前内皮素原1;内皮素1;前内皮素原1
产品基因名称 :
ET-1
其他基因名称 :
EDN1;EDN1;ET1;PPET1;HDLCQ7;PPET1;ET-1
UniProt数据库进入名 :
EDN1_HUMAN
反应物种 :
人类
特异性 :
No significant cross-reactivity or interference between this analyte and analogues is observed.
储存稳定性 :
Store all reagents at 2-8 degree C
其它信息1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich. Detection Range: 6.25 pg/ml - 200 pg/ml. Sensitivity: 1.0 pg/ml.
其他信息2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
产品描述 :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of EDN1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
NCBI GI登录号 :
556203
NCBI登录号 :
AAA52339.1
UniProt数据库登录号 :
P05305
NCBI分子量 :
24,425 Da
NCBI信号通路 :
Class A/1 (Rhodopsin-like Receptors) Pathway (106357); EGFR-dependent Endothelin Signaling Events Pathway (138037); Endothelin Pathway (672453); Endothelins Pathway (137958); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); HIF-1 Signaling Pathway (695200); HIF-1-alpha Transcription Factor Network Pathway (138045)
NCBI总结 :
The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
UniProt数据库总结 :
EDN1: Endothelins are endothelium-derived vasoconstrictor peptides. Belongs to the endothelin/sarafotoxin family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 6p24.1. Cellular Component: extracellular space; cytoplasm; extracellular region. Molecular Function: protein binding; hormone activity; endothelin B receptor binding; cytokine activity; endothelin A receptor binding. Biological Process: response to nicotine; positive regulation of JNK activity; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of nitric oxide biosynthetic process; regulation of systemic arterial blood pressure by endothelin; heart development; response to lipopolysaccharide; middle ear morphogenesis; prostaglandin biosynthetic process; sensory perception of pain; positive regulation of MAP kinase activity; negative regulation of cAMP biosynthetic process; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; cell-cell signaling; negative regulation of nitric-oxide synthase biosynthetic process; protein kinase C activation; cell growth; neutrophil chemotaxis; rhythmic excitation; positive regulation of mitosis; negative regulation of blood coagulation; positive regulation of heart rate; respiratory gaseous exchange; response to testosterone stimulus; peptide hormone secretion; response to amino acid stimulus; leukocyte activation; patterning of blood vessels; membrane depolarization; protein kinase C deactivation; regulation of vasoconstriction; positive regulation of transcription from RNA polymerase II promoter; response to activity; superoxide release; positive regulation of odontogenesis; epithelial fluid transport; phosphoinositide 3-kinase cascade; neural crest cell development; G-protein signaling, phospholipase D activating pathway; positive regulation of cell size; positive regulation of smooth muscle cell proliferation; negative regulation of hormone secretion; negative regulation of cellular protein metabolic process; glucose transport; negative regulation of transcription from RNA polymerase II promoter; vein smooth muscle contraction; histamine secretion; nitric oxide transport; positive regulation of cell proliferation; regulation of pH; positive regulation of smooth muscle contraction; artery smooth muscle contraction; vasoconstriction; inositol phosphate-mediated signaling; in utero embryonic development; positive regulation of hormone secretion; calcium-mediated signaling; multicellular organismal aging; body fluid secretion; G-protein coupled receptor protein signaling pathway; dorsal/ventral pattern formation; cartilage development; response to ozone; positive regulation of prostaglandin secretion; maternal process involved in parturition; regulation of sensory perception of pain; positive regulation of cell migration. Disease: Question Mark Ears, Isolated; Auriculocondylar Syndrome 3
尺寸1 :
48-Strip-Wells
价格1 :
435美元
尺寸2 :
96-Strip-Wells
价格2 :
600
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。