ELISA/assay

Mouse Dynamin-like 120 kDa protein, mitochondrial, OPA1 ELISA Kit

MBS9325925

48-Strip-Wells

470美元

酶联免疫吸附试剂盒

Mouse Dynamin-like 120 kDa protein, mitochondrial, OPA1 ELISA Kit

[optic atrophy 1 (autosomal dominant)]

[Mouse Dynamin-like 120 kDa protein; mitochondrial (OPA1) ELISA kit; FLJ12460; KIAA0567; MGM1; NPG; NTG; largeG; mitochondrial dynamin-like GTPase; optic atrophy 1; optic atrophy 1 (autosomal dominant)]

[dynamin-like 120 kDa protein, mitochondrial isoform 2; Dynamin-like 120 kDa protein, mitochondrial; Large GTP-binding protein; LargeG; Optic atrophy protein 1 homologCleaved into the following chain:Dynamin-like 120 kDa protein, form S1]

[OPA1]

[Opa1; LargeG]

OPA1_MOUSE

小鼠

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.5 ng/ml - 16 ng/mL. Sensitivity: 0.1 ng/mL

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of OPA1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

19526960

NP_598513.1

NM_133752.3

P58281

111,339 Da

OPA1: a dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space. Defects in OPA1 are the cause of optic atrophy 1 and deafness. Eight splice-variant isoforms have been described. Protein type: Mitochondrial; Apoptosis; Membrane protein, integral; Hydrolase; EC 3.6.5.5. Cellular Component: nucleoplasm; mitochondrial crista; mitochondrial outer membrane; membrane; mitochondrion; cytoplasm; mitochondrial inner membrane; dendrite; integral to membrane; mitochondrial intermembrane space. Molecular Function: GTPase activity; protein binding; GTP binding; hydrolase activity; nucleotide binding. Biological Process: inner mitochondrial membrane organization and biogenesis; positive regulation of neuron maturation; mitochondrion organization and biogenesis; mitochondrial genome maintenance; visual perception; mitochondrial fusion; apoptosis; response to stimulus; neural tube closure

48-Strip-Wells

470美元

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095