ELISA/assay

Human Transforming protein RhoA, RHOA ELISA Kit

MBS9335451

48-Strip-Wells

435美元

酶联免疫吸附试剂盒

Human Transforming protein RhoA, RHOA ELISA Kit

ras homolog gene family, member A

Human Transforming protein RhoA (RHOA) ELISA kit; ARH12; ARHA; RHO12; RHOH12; Aplysia ras-related homolog 12; oncogene RHO H12; small GTP binding protein RhoA; ras homolog gene family; member A

transforming protein RhoA; Transforming protein RhoA; transforming protein RhoA; h12; oncogene RHO H12; rho cDNA clone 12; Aplysia ras-related homolog 12; small GTP binding protein RhoA; ras homolog gene family, member A; ras homolog family member A; Rho cDNA clone 12; h12

RHOA

RHOA;RHOA;ARHA;ARH12;RHO12;RHOH12;ARH12;ARHA;RHO12;h12

RHOA_HUMAN

人类

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of RHOA (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

10835049

NP_001655.1

NM_001664.2

P61586

21,768 Da

AGE/RAGE Pathway (698754); Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Alpha6-Beta4 Integrin Signaling Pathway (198807); Androgen Receptor Signaling Pathway (198806); Arf6 Downstream Pathway (138038); Aurora B Signaling Pathway (138080); Axon Guidance Pathway (83065); Axon Guidance Pathway (476); Axon Guidance Pathway (105688)

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]

RHOA: a small G protein of the Rho family. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Controls the reorganization of actins into podosomes. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. Protein type: G protein, monomeric; G protein, monomeric, Rho; Motility/polarity/chemotaxis; Oncoprotein; G protein. Chromosomal Location of Human Ortholog: 3p21.3. Cellular Component: apical junction complex; cytoskeleton; focal adhesion; lamellipodium; plasma membrane; midbody; cell cortex; cell junction; cytosol; cleavage furrow. Molecular Function: GTPase activity; protein binding; GTP binding; myosin binding. Biological Process: axon guidance; viral reproduction; nerve growth factor receptor signaling pathway; metabolic process; negative chemotaxis; positive regulation of NF-kappaB import into nucleus; regulation of axonogenesis; regulation of cell migration; Rho protein signal transduction; regulation of osteoblast proliferation; substantia nigra development; small GTPase mediated signal transduction; transforming growth factor beta receptor signaling pathway; positive regulation of stress fiber formation; ephrin receptor signaling pathway; negative regulation of axonogenesis; positive regulation of cytokinesis; platelet activation; apical junction assembly; positive regulation of I-kappaB kinase/NF-kappaB cascade; phosphoinositide-mediated signaling; regulation of small GTPase mediated signal transduction; positive regulation of axonogenesis; actin cytoskeleton organization and biogenesis; blood coagulation; positive regulation of neuron differentiation; vascular endothelial growth factor receptor signaling pathway

48-Strip-Wells

435美元

96-Strip-Wells

600