产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
Human Lysine-specific demethylase 2B, KDM2B ELISA Kit
目录 :
MBS9337541
规格 :
48-Strip-Wells
价格 :
470美元
更多信息或购买 :
产品信息
目录号 :
MBS9337541
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
Human Lysine-specific demethylase 2B, KDM2B ELISA Kit
产品简称 :
[lysine (K) -specific demethylase 2B]
产品名称同义词 :
[Human Lysine-specific demethylase 2B (KDM2B) ELISA kit; CXXC2; FBXL10; Fbl10; JHDM1B; PCCX2; F-box and leucine-rich repeat protein 10; JEMMA (Jumonji domain; EMSY-interactor; methyltransferase motif) protein; jumonji C domain-containing histone demethylase; lysine (K) -specific demethylase 2B]
其他名称 :
[lysine-specific demethylase 2B isoform b; Lysine-specific demethylase 2B; lysine-specific demethylase 2B; F-box protein FBL10; F-box/LRR-repeat protein 10; CXXC-type zinc finger protein 2; protein-containing CXXC domain 2; [Histone-H3]-lysine-36 demethylase 1B; F-box and leucine-rich repeat protein 10; jumonji C domain-containing histone demethylase 1B; jmjC domain-containing histone demethylation protein 1B; JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein; lysine (K)-specific demethylase 2B; CXXC-type zinc finger protein 2; F-box and leucine-rich repeat protein 10; F-box protein FBL10; F-box/LRR-repeat protein 10; JmjC domain-containing histone demethylation protein 1B; Jumonji domain-containing EMSY-interactor methyltransferase motif protein; Protein JEMMA; Protein-containing CXXC domain 2; [Histone-H3]-lysine-36 demethylase 1B]
产品基因名称 :
[KDM2B]
其他基因名称 :
[KDM2B;KDM2B;CXXC2;Fbl10;PCCX2;FBXL10;JHDM1B;CXXC2;FBL10;FBXL10;JHDM1B;PCCX2;蛋白JEMMA]
UniProt数据库进入名 :
KDM2B_HUMAN
反应物种 :
人类
特异性 :
No significant cross-reactivity or interference between this analyte and analogues is observed.
储存稳定性 :
Store all reagents at 2-8 degree C
其它信息1 :
Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
其他信息2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
产品描述 :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of KDM2B (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
NCBI GI登录号 :
54112380
NCBI登录号 :
NP_001005366.1
NCBI基因登录号 :
NM_001005366.1
UniProt数据库登录号 :
Q8NHM5
NCBI分子量 :
152,615 Da
NCBI总结 :
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
FBXL10: Histone demethylase that demethylates Lys-4 and Lys- 36 of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 Lys-4 and dimethylated H3 Lys-36 residue while it has weak or no activity for mono- and tri-methylated H3 Lys-36 . Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Belongs to the JHDM1 histone demethylase family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Oxidoreductase; DNA-binding; EC 1.14.11.27; Nucleolus; Demethylase. Chromosomal Location of Human Ortholog: 12q24.31. Cellular Component: nucleoplasm; nucleolus; PcG protein complex; nucleus. Molecular Function: rRNA binding; protein binding; histone demethylase activity; DNA binding; zinc ion binding; histone demethylase activity (H3-K36 specific). Biological Process: midbrain-hindbrain boundary morphogenesis; establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; fourth ventricle development; negative regulation of transcription from RNA polymerase II promoter; third ventricle development; initiation of neural tube closure; histone demethylation; midbrain development; forebrain development; spermatogenesis; negative regulation of neuron apoptosis; embryonic camera-type eye morphogenesis; lateral ventricle development; hindbrain development
尺寸1 :
48-Strip-Wells
价格1 :
470美元
尺寸2 :
96-Strip-Wells
价格2 :
680
size3 :
5x96-Strip-Wells
价格3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。