ELISA/assay

Human MAP kinase-interacting serine/threonine-protein kinase 1, MKNK1 ELISA Kit

MBS9340465

48-Strip-Wells

470美元

酶联免疫吸附试剂盒

Human MAP kinase-interacting serine/threonine-protein kinase 1, MKNK1 ELISA Kit

[MAP kinase interacting serine/threonine kinase 1]

[Human MAP kinase-interacting serine/threonine-protein kinase 1 (MKNK1) ELISA kit; RP11-49P4.3; MNK1; MAP kinase interacting kinase 1; MAP kinase-interacting serine/threonine kinase 1; MAP kinase interacting serine/threonine kinase 1]

[MAP kinase-interacting serine/threonine-protein kinase 1 isoform 3; MAP kinase-interacting serine/threonine-protein kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MAPK signal-integrating kinase 1; MAP kinase signal-integrating kinase 1; MAP kinase interacting serine/threonine kinase 1; MAP kinase signal-integrating kinase 1; MAPK signal-integrating kinase 1; Mnk1]

[MKNK1]

[MKNK1; MKNK1; MNK1; MNK1; MAPK signal-integrating kinase 1; Mnk1]

MKNK1_HUMAN

人类

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MKNK1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

207113186

NP_001129025.1

NM_001135553.2

Q9BUB5

51,342 Da

IL-2 Signaling Pathway (198885); Insulin Signaling Pathway (83090); Insulin Signaling Pathway (501); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Negative Regulation Of FGFR Signaling Pathway (477118); Signal Transduction Pathway (477114); Signaling By FGFR Pathway (106343); Signaling Mediated By P38-alpha And P38-beta Pathway (138012); Spry Regulation Of FGF Signaling Pathway (477119)

This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012]

Mnk1: a CAM kinase of the MAPKKAPK family that can regulate translation. Following activation by MAP kinases, Mnk1 phosphorylates eIF4E at Ser209, increasing its affinity for the 7-methylguanosine-containing mRNA cap. Two MAPK phosphorylation sites in mouse Mnk1 (Thr197 and Thr202) are essential for its kinase activity. Three alternatively spliced human isoforms have been described. Protein type: Kinase, protein; Translation; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; CAMK group; MAPKAPK family; MNK subfamily. Chromosomal Location of Human Ortholog: 1p33. Cellular Component: cytosol; nucleus. Molecular Function: protein serine/threonine kinase activity; protein binding; ATP binding. Biological Process: peptidyl-serine phosphorylation; fibroblast growth factor receptor signaling pathway; protein amino acid phosphorylation; response to salt stress; regulation of translational initiation

48-Strip-Wells

470美元

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095