抗体

ADRA1D抗体

MBS9383436

0.1毫升

440美元

多克隆

兔

未共轭

酶联免疫吸附测定, 免疫组化, 免疫细胞化学

抗体

ADRA1D抗体

[ADRA1D]

[Alpha-1D adrenergic receptor, Alpha 1D-adrenoceptor, Alpha 1D-adrenoreceptor, Alpha-1A adrenergic receptor, Alpha-adrenergic receptor 1a, ADRA1D, ADRA1A]

[alpha-1D adrenergic receptor; Alpha-1D adrenergic receptor; alpha-1D adrenergic receptor; adrenoceptor alpha 1D; Alpha-1A adrenergic receptor; Alpha-1D adrenoreceptor; Alpha-1D adrenoceptor; Alpha-adrenergic receptor 1a]

[ADRA1D]

[ADRA1D; ADRA1D; DAR; ADRA1; ADRA1A; ADRA1R; ALPHA1; dJ779E11.2; ADRA1A; Alpha-1D adrenoceptor]

多克隆

兔

Human (Identities = 100%, Positives = 100%)

572

ADRA1D抗体检测内生水平总数ADRA1D蛋白

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

1.0毫克/毫升

Store at -20 degree C/1 year

免疫组化, IF, 酶联免疫吸附测定

IHC: 1:50~1:100。 IF: 1:100~1:500。 ELISA: 1:40000

免疫组化

免疫荧光

Immunogen: The antiserum was produced against synthesized peptide derived from internal of human ADRA1D.

4501957

NP_000669.1

NM_000678.3

P25100

Adrenergic Signaling In Cardiomyocytes Pathway (908257); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Adrenoceptors Pathway (106365); Amine Ligand-binding Receptors Pathway (106363); Calcium Regulation In The Cardiac Cell Pathway (198906); Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764)

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region. [provided by RefSeq, Jul 2008]

ADRA1D: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1D sub-subfamily. Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR. Chromosomal Location of Human Ortholog: 20p13. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: protein binding. Biological Process: cell proliferation; cell-cell signaling; DNA metabolic process; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); multicellular organismal development; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure; positive regulation of cell proliferation; positive regulation of smooth muscle contraction; positive regulation of vasoconstriction

0.1毫升

440美元

0.2毫升

715