产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
CD68抗体
目录 :
MBS9384073
规格 :
0.1毫升
价格 :
440美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
图像
图像 1 :
Western blot analysis of CD68 using HT-29 whole cell lysates
图像 2 :
Western blot analysis of CD68 using HT-29 whole cell lysates
产品信息
目录号 :
MBS9384073
产品类型 :
抗体
产品全称 :
CD68抗体
产品简称 :
[CD68]
其他名称 :
[macrosialin isoform B; Macrosialin; macrosialin; CD68 molecule; Gp110; CD_antigen: CD68]
产品基因名称 :
[CD68]
其他基因名称 :
[CD68;CD68;GP110;LAMP4;SCARD1]
克隆性 :
多克隆
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
327
特异性 :
ATF-4(磷酸化Ser219)Ab检测内生水平总数ATF-4(磷酸化Ser219)
纯度 :
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (ThermoFisher Scientific).
浓度 :
1毫克/毫升
储存稳定性 :
Store at -20°C. Stable for 12 months from date of receipt.
检测过的应用 :
免疫印迹(免疫印迹), 免疫组化(免疫组化)
应用笔记 :
免疫印迹(免疫印迹)1:1000-3000。 免疫组化(免疫组化)1:200
image1头 :
免疫印迹(免疫印迹)
image2头 :
免疫印迹(免疫印迹)
NCBI GI登录号 :
91199550
NCBI登录号 :
NP_001035148.1
NCBI基因登录号 :
NM_001040059.1
UniProt数据库登录号 :
P34810
NCBI分子量 :
36 kDa
NCBI信号通路 :
溶体通路(99052);溶体通路(96865)
NCBI总结 :
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
CD68: Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. Belongs to the LAMP family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cell surface; Membrane protein, integral. Chromosomal Location of Human Ortholog: 17p13.1. Cellular Component: membrane
尺寸1 :
0.1毫升
价格1 :
440美元
尺寸2 :
0.2毫升
价格2 :
715
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。