产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
白细胞介素-8抗体
目录 :
MBS9385550
规格 :
0.1毫升
价格 :
440美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS9385550 图像 1
Western blot analysis of extracts of Mouse liver, using IL8 Ab. The lane on the left is treated with the antigen-specific peptide.
图像 2 :
MyBioSource MBS9385550 图像 2
1/100 staining human kidney tissues sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the Ab for 1.5 hours at129
产品信息
目录号 :
MBS9385550
产品类型 :
抗体
产品全称 :
白细胞介素-8抗体
产品简称 :
[白细胞介素-8]
其他名称 :
[interleukin-8; Interleukin-8; interleukin-8; C-X-C motif chemokine ligand 8; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1]
产品基因名称 :
[白细胞介素-8]
其他基因名称 :
[CXCL8;CXCL8;白细胞介素-8;NAF;GCP1;LECT;LUCT;NAP1;GCP-1;LYNAP;MDNCF;MONAP;NAP-1;白细胞介素-8;IL-8;GCP-1;MDNCF;MONAP;NAP-1;LYNAP;NAF]
克隆性 :
多克隆
宿主 :
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
99
特异性 :
白细胞介素-8 Ab检测内生水平总数白细胞介素-8
纯度 :
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
浓度 :
1.0毫克/毫升
储存稳定性 :
Store at -20°C.Stable for 12 months from date of receipt.
检测过的应用 :
免疫印迹(免疫印迹), 免疫组化(免疫组化)
应用笔记 :
免疫印迹1:500-1:2000。 免疫组化1:50-1:200
image1头 :
免疫印迹
image2头 :
免疫组化
其它信息1 :
Immunogen: A specific peptide ofhuman IL8. Subcellular Location: Secreted. Tissue Specificity: By ER stress in a DDIT3/CHOP-dependent manner. Similarity: Belongs to the intercrine alpha (chemokine CxC) family.
其他信息2 :
Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
NCBI GI登录号 :
10834978
NCBI登录号 :
NP_000575.1
NCBI基因登录号 :
NM_000584.3
UniProt数据库登录号 :
P10145
NCBI分子量 :
11 kDa
NCBI信号通路 :
ATF-2 Transcription Factor Network Pathway (138006); Activation Of Genes By ATF4 Pathway (530772); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Bladder Cancer Pathway (83115); Bladder Cancer Pathway (527); Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway (137993); Chagas Disease (American Trypanosomiasis) Pathway (147809); Chagas Disease (American Trypanosomiasis) Pathway (147795); Chemokine Receptors Bind Chemokines Pathway (106359)
NCBI总结 :
The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
IL8: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. Belongs to the intercrine alpha (chemokine CxC) family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cytokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: extracellular region. Molecular Function: chemokine activity; interleukin-8 receptor binding; protein binding. Biological Process: angiogenesis; calcium-mediated signaling; cell cycle arrest; cell motility; chemotaxis; embryonic gut development; G-protein coupled receptor protein signaling pathway; immune response; induction of positive chemotaxis; inflammatory response; negative regulation of cell proliferation; negative regulation of G-protein coupled receptor protein signaling pathway; neutrophil activation; neutrophil chemotaxis; positive regulation of angiogenesis; receptor internalization; regulation of cell adhesion; regulation of retroviral genome replication; response to molecule of bacterial origin; signal transduction
尺寸1 :
0.1毫升
价格1 :
440美元
尺寸2 :
0.2毫升
价格2 :
715
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。