产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
SLPI抗体
目录 :
MBS9408899
规格 :
0.1毫升
价格 :
320美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 酶免疫法
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS9408899 图像 1
Western blot analysis of SLPI in A-20 cell lysate with SLPI antibody at 2 ug/mL.
产品信息
目录号 :
MBS9408899
产品类型 :
抗体
产品全称 :
SLPI抗体
产品简称 :
[SLPI]
产品名称同义词 :
[mSLPI, Secretory leukocyte protease inhibitor, HUSI]
其他名称 :
[antileukoproteinase; Antileukoproteinase; antileukoproteinase; secretory leukocyte peptidase inhibitor; Secretory leukocyte protease inhibitor]
产品基因名称 :
[SLPI]
其他基因名称 :
[Slpi; Slpi; ALP]
UniProt数据库进入名 :
SLPI_MOUSE
克隆性 :
多克隆
宿主 :
反应物种 :
小鼠
序列长度 :
131
纯度 :
Affinity chromatography purified via peptide column
形式 :
用品在PBS含0.02% 叠氮化钠
浓度 :
1毫克/毫升
储存稳定性 :
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)
image1头 :
免疫印迹(免疫印迹)
其它信息1 :
Immunogen Type: Peptide. Immunogen Description: Raised against a 17 amino acid peptide from near the center of mouse SLPI.
其他信息2 :
Target Name: SLPI
产品种类 :
总数蛋白Ab
产品描述 :
Secretory leukocyte protease inhibitor (SLPI) is produced at mucosal surfaces, primarily the upper respiratory tract and is thought to play an important role in the antiprotease defense mechanism of the lung. SLPI forms inhibitory complexes with numerous proteolytic enzymes such as neutrophil elastase, and has been shown to possess anti-inflammatory, anti-viral, and antibacterial activities. Its expression in oral epithelial cells is stimulated by HIV-1 gp120, suggesting that SLPI is a component of the oral mucosal response to HIV-1. In peripheral blood monocytes, SLPI can inhibit NF-kB activation by inhibiting IkB degradation in the cytoplasm and competing for NF-kB binding sites in the nucleus. This attenuation of the inflammatory response may also act to suppress liver metastases and other cancer cell invasions, but promote blood-borne metastasis via an invasion-independent pathway.
NCBI GI登录号 :
6755574
NCBI登录号 :
NP_035544
NCBI基因登录号 :
NM_011414.3
NCBI分子量 :
14,308 Da
UniProt数据库总结 :
SLPI: Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. May prevent elastase-mediated damage to oral and possibly other mucosal tissues. Protein type: Inhibitor; Secreted; Secreted, signal peptide. Cellular Component: extracellular matrix; extracellular region. Molecular Function: serine-type endopeptidase inhibitor activity; enzyme binding; protease inhibitor activity; endopeptidase inhibitor activity. Biological Process: negative regulation of viral genome replication; negative regulation of peptidase activity; negative regulation of protein binding
尺寸1 :
0.1毫升
价格1 :
320美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。