产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
ITGB2抗体
目录 :
MBS9507501
规格 :
0.05毫克
价格 :
245美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 酶免疫法
更多信息或购买 :
图像
图像 1 :
Western Blot analysis of extracts from HeLa cells using ITGB2 Antibody.
产品信息
目录号 :
MBS9507501
产品类型 :
抗体
产品全称 :
ITGB2抗体
产品简称 :
[ITGB2]
产品名称同义词 :
[ITGB2; CD18; MFI7; Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; CD18]
其他名称 :
[integrin beta-2 isoform 1; Integrin beta-2; integrin beta-2; integrin subunit beta 2; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; CD_antigen: CD18]
产品基因名称 :
[ITGB2]
其他基因名称 :
[ITGB2;ITGB2;LAD;CD18;MF17;MFI7;LCAMB;LFA-1;MAC-1;CD18;MFI7]
克隆性 :
多克隆
宿主 :
兔
反应物种 :
人类
序列长度 :
769
特异性 :
ITGB2抗体检测内生水平ITGB2蛋白
纯度 :
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
形式 :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
储存稳定性 :
Store at -20 degree C for 1 year.
检测过的应用 :
免疫印迹(免疫印迹), 酶联免疫吸附测定(EIA)
应用笔记 :
WB: 1:500~1:1000。 ELISA: 1:10000
image1头 :
免疫印迹(免疫印迹)
其它信息1 :
Target Modification: Unmodified/Total
其他信息2 :
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human ITGB2. Immunogen Range: 621-670
NCBI GI登录号 :
735367775
NCBI登录号 :
NP_000202.3
NCBI基因登录号 :
NM_000211.4
UniProt数据库登录号 :
P05107
NCBI分子量 :
84 kDa
NCBI信号通路 :
Adaptive Immune System Pathway (1269171); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); CXCR3-mediated Signaling Events Pathway (138011); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Surface Interactions At The Vascular Wall Pathway (1269373); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); Extracellular Matrix Organization Pathway (1270244)
NCBI总结 :
This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
UniProt数据库总结 :
Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity (PubMed:15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:11812992, PubMed:28807980). Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation (PubMed:18587400). Integrin ITGAL/ITGB2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590). In association with alpha subunit ITGAM/CD11b, required for CD177-PRTN3-mediated activation of TNF primed neutrophils (PubMed:21193407).
尺寸1 :
0.05毫克
价格1 :
245美元
尺寸2 :
0.1毫克
价格2 :
335
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。