产品简要
公司名称 :
MyBioSource
产品类型 :
蛋白
产品名称 :
Recombinant Human DNA-3-methyladenine glycosylase
目录 :
MBS954215
规格 :
0.05毫克(大肠杆菌)
价格 :
190美元
更多信息或购买 :
产品信息
目录号 :
MBS954215
产品类型 :
重组蛋白
产品全称 :
Recombinant Human DNA-3-methyladenine glycosylase
产品简称 :
DNA-3-methyladenine glycosylase
产品名称同义词 :
3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; ADPGN-methylpurine-DNA glycosylase
其他名称 :
DNA-3-methyladenine glycosylase isoform b; DNA-3-methyladenine glycosylase; DNA-3-methyladenine glycosylase; N-methylpurine DNA glycosylase; 3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; ADPG; N-methylpurine-DNA glycosylase
产品基因名称 :
MPG
其他基因名称 :
MPG; MPG; AAG; MDG; ADPG; APNG; Mid1; anpg; PIG11; PIG16; CRA36.1; AAG; ANPG; MID1
UniProt数据库进入名 :
3 MG_HUMAN
宿主 :
E Coli or Yeast or Baculovirus or Mammalian Cell
序列位置 :
13-298
序列长度 :
293
序列 :
MPARSGAQFCRRMGQKKQRPARAGQPHSSSDAAQAPAEQ
PHSSSDAAQAPCPRERCLGPPTTPGPYRSIYFSSPKGHL
TRLGLEFFDQPAVPLARAFLGQVLVRRLPNGTELRGRIV
ETEAYLGPEDEAAHSRGGRQTPRNRGMFMKPGTLYVYII
YGMYFCMNISSQGDGACVLLRALEPLEGLETMRQLRSTL
RKGTASRVLKDRELCSGPSKLCQALAINKSFDQRDLAQD
EAVWLERGPLEPSEPAVVAAA
纯度 :
Greater than 90% as determined by SDS-PAGE.
形式 :
Liquid containing glycerol; lyophilization may be available upon request.
储存稳定性 :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
产品种类 :
Epigenetics and Nuclear Signaling
产品描述 :
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
产品引用 :
Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16.Samson L., Derfler B., Boosalis M., Call K.Proc. Natl. Acad. Sci. U.S.A. 88:9127-9131(1991) Structure of the human 3-methyladenine DNA glycosylase gene and localization close to the 16p telomere.Vickers M.A., Vyas P., Harris P.C., Simmons D.L., Higgs D.R.Proc. Natl. Acad. Sci. U.S.A. 90:3437-3441(1993) Identification of a human cell proliferation gene 11.Kim J.W.NIEHS SNPs programSequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16.Daniels R.J., Peden J.F., Lloyd C., Horsley S.W., Clark K., Tufarelli C., Kearney L., Buckle V.J., Doggett N.A., Flint J., Higgs D.R.Hum. Mol. Genet. 10:339-352(2001) The sequence and analysis of duplication-rich human chromosome 16.Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A.Nature 432:988-994(2004)
NCBI GI登录号 :
62632765
NCBI登录号 :
NP_001015052.1
NCBI基因登录号 :
NM_001015052.2
UniProt数据库登录号 :
P29372
NCBI分子量 :
34.2kD
NCBI信号通路 :
Base Excision Repair Pathway (1270351); Base Excision Repair Pathway (83043); Base Excision Repair Pathway (451); Base-Excision Repair, AP Site Formation Pathway (1270352); Cleavage Of The Damaged Purine Pathway (1270355); DNA Repair Pathway (1270350); Depurination Pathway (1270353); Displacement Of DNA Glycosylase By APEX1 Pathway (1270360); Recognition And Association Of DNA Glycosylase With Site Containing An Affected Purine Pathway (1270354); Resolution Of Abasic Sites (AP Sites) Pathway (1270359)
UniProt数据库总结 :
MPG: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions. Belongs to the DNA glycosylase MPG family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Nuclear receptor co-regulator; Hydrolase; EC 3.2.2.21. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: nucleoplasm. Molecular Function: alkylbase DNA N-glycosylase activity; damaged DNA binding; DNA-3-methyladenine glycosylase I activity; protein binding. Biological Process: base-excision repair; base-excision repair, AP site formation; depurination; DNA dealkylation; DNA repair
尺寸1 :
0.05毫克(大肠杆菌)
价格1 :
190美元
尺寸2 :
0.2毫克(大肠杆菌)
价格2 :
460
size3 :
0.5毫克(大肠杆菌)
价格3 :
750
size4 :
0.05毫克(杆状病毒)
price4 :
1055
size5 :
1毫克(大肠杆菌)
price5 :
1180
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。