产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
ZEB2抗体
目录 :
MBS9601451
规格 :
0.1毫升
价格 :
240美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 酶免疫法
更多信息或购买 :
MyBioSource 产品网页
图像
图像 1 :
MyBioSource MBS9601451 图像 1
MBS9601451 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
图像 2 :
MyBioSource MBS9601451 图像 2
MBS9601451 at 1/100 staining human liver tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
图像 3 :
MyBioSource MBS9601451 图像 3
Western blot analysis of ZEB2 expression in HepG2 cell lysate, The lane on the left is treated with the antigen-specific peptide.
产品信息
目录号 :
MBS9601451
产品类型 :
抗体
产品全称 :
ZEB2抗体
产品简称 :
[ZEB2]
产品名称同义词 :
[FLJ42816; HSPC082; KIAA0569; SIP 1; SIP1; Smad-interacting protein 1; SMADIP 1; SMADIP1; ZEB 2; Zeb2; ZEB2_HUMAN; Zfhx1b; ZFHX1B protein; Zfx1b; Zinc finger E box binding protein 2; Zinc finger E-box-binding homeobox 2; Zinc finger homeobox 1b; zinc finger homeobox protein 1; Zinc finger homeobox protein 1b]
其他名称 :
[zinc finger E-box-binding homeobox 2 isoform 2; Zinc finger E-box-binding homeobox 2; zinc finger E-box-binding homeobox 2; zinc finger E-box binding homeobox 2; Smad-interacting protein 1; SMADIP1; Zinc finger homeobox protein 1b]
产品基因名称 :
[ZEB2]
其他基因名称 :
[ZEB2;ZEB2;SIP1;SIP-1;ZFHX1B;HSPC082;SMADIP1;KIAA0569;SIP1;ZFHX1B;ZFX1B;SMADIP1]
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
1190
特异性 :
ZEB2抗体检测内生水平总数ZEB2
纯度 :
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
形式 :
磷酸盐缓冲液, pH值7.4, 150mM氯化钠, 0.02% 叠氮化钠和50% 甘油
浓度 :
1毫克/毫升
储存稳定性 :
Store at -20 degree C. Stable for 12 months from date of receipt.
检测过的应用 :
Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
应用笔记 :
WB: 1:500-1:2000。 IHC: 1:50-1:200。 IF/ICC: 1:100-1:500
image1头 :
免疫荧光(IF)
image2头 :
免疫组化(免疫组化)
image3头 :
免疫印迹(免疫印迹)
其它信息1 :
Immunogen: A synthesized peptide derived from human ZEB2 corresponding to a region within N-terminal amino acids.
产品描述 :
Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin. Similarity: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.
产品引用 :
YaoduWang, ZhiyangWu, LikuanHu; Journal: EUR J PHARMACOL. The regulatory effects of metformin on the [SNAIL/miR-34]:[ZEB/miR-200] system in the epithelial-mesenchymal transition(EMT) for colorectal cancer(CRC).
NCBI GI登录号 :
284413746
NCBI登录号 :
NP_001165124.1
NCBI基因登录号 :
NM_001171653.1
UniProt数据库登录号 :
O60315
NCBI分子量 :
136 kDa
NCBI信号通路 :
TGF Beta Signaling Pathway (198810); TGF-beta Receptor Signaling Pathway (198774)
NCBI总结 :
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]
UniProt数据库总结 :
Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin.
尺寸1 :
0.1毫升
价格1 :
240美元
尺寸2 :
0.2毫升
价格2 :
280
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。