抗体

REV1抗体

MBS9604095

0.1毫升

240美元

多克隆

兔

未共轭

人类, 小鼠

免疫印迹, 酶联免疫吸附测定, 免疫组化, 酶免疫法

抗体

REV1抗体

[REV1]

[AIBP 80; AIBP80; Alpha integrin binding protein 80; Alpha integrin-binding protein 80; DNA repair protein REV 1; DNA repair protein REV1; FLJ21523; MGC163283; MGC26225; REV 1 (yeast homolog) like; REV 1; REV 1 homolog; REV 1 like; REV 1 protein; REV 1L; REV1 (yeast homolog) like; REV1; REV1 homolog (S. cerevisiae); REV1 homolog; REV1 like (yeast); REV1 like; Rev1 like terminal deoxycytidyl transferase; REV1 protein; Rev1-like terminal deoxycytidyl transferase; REV1_HUMAN; REV1L]

[DNA repair protein REV1 isoform 2; DNA repair protein REV1; DNA repair protein REV1; REV1, DNA directed polymerase; Alpha integrin-binding protein 80; AIBP80; Rev1-like terminal deoxycytidyl transferase]

[REV1]

[REV1;REV1;REV1L;AIBP80;REV1L;AIBP80]

多克隆

IgG

兔

人类, 小鼠

1250

REV1抗体检测内生水平总数REV1

The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.

液体。 磷酸盐缓冲液, pH值7.4, 150mM氯化钠, 0.02% 叠氮化钠和50% 甘油

1毫克/毫升

免疫印迹(免疫印迹), 免疫组化(免疫组化), 酶联免疫吸附测定(EIA)

WB: 1:500-1:2000。 IHC: 1:50-1:200

免疫组化(免疫组化)

免疫印迹(免疫印迹)

Immunogen: A synthesized peptide. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous. Predicted Cross Reactivity : Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken, Xenopus . Similarity: Pig (100%), Zebrafish (90%), Bovine (100%), Horse (100%), Sheep (100%), Dog (100%), Chicken (100%), Xenopus (100%)

Conjugation: Unconjugated

Description: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. Subunit Structure: Monomer. Interacts with the DNA polymerase zeta which is composed of REV3L and MAD2L2; the interaction with MAD2L2 is direct and requires that REV3L is in its closed conformation. Interacts with POLH, POLI and POLK. May bind ITGA3. Interacts with FAAP20/C1orf86. Similarity: The C-terminal domain is necessary for protein interactions. Belongs to the DNA polymerase type-Y family.

84043967

NP_001032961.1

NM_001037872.2

Q9UBZ9

Observed: 138 kDa. Predicted: 139 kDa

DNA Damage Bypass Pathway (105852); DNA Repair Pathway (105837); Fanconi Anemia Pathway (377262); Fanconi Anemia Pathway (377128); Translesion Synthesis By DNA Polymerases Bypassing Lesion On DNA Template Pathway (105853); Translesion Synthesis By HREV1 Pathway (105854)

This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. [provided by RefSeq, Mar 2016]

Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.

0.1毫升

240美元

0.2毫升

280