产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
MLH3抗体
目录 :
MBS9605078
规格 :
0.1毫升
价格 :
240美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 酶免疫法
更多信息或购买 :
MyBioSource 产品网页
图像
图像 1 :
MyBioSource MBS9605078 图像 1
MBS9605078 staining K562 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
图像 2 :
MyBioSource MBS9605078 图像 2
MBS9605078 at 1/100 staining Mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
图像 3 :
MyBioSource MBS9605078 图像 3
Western blot analysis of extracts from K562, using MLH3 antibody.
产品信息
目录号 :
MBS9605078
产品类型 :
抗体
产品全称 :
MLH3抗体
产品简称 :
[MLH3]
产品名称同义词 :
[DNA mismatch repair protein Mlh3; HNPCC 7; HNPCC; HNPCC7; MGC138372; Mismatch repair gene MLH 3; Mismatch repair gene MLH3; MLH 3; MLH3; MLH3_HUMAN; MutL homolog 3 (E. coli); MutL homolog 3; MutL protein homolog 3; S240II117]
其他名称 :
[DNA mismatch repair protein Mlh3 isoform 1; DNA mismatch repair protein Mlh3; DNA mismatch repair protein Mlh3; mutL homolog 3; MutL protein homolog 3]
产品基因名称 :
[MLH3]
其他基因名称 :
[MLH3;MLH3;HNPCC7]
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
1453
特异性 :
MLH3抗体检测内生水平总数MLH3
纯度 :
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
形式 :
磷酸盐缓冲液, pH值7.4, 150mM氯化钠, 0.02% 叠氮化钠和50% 甘油
储存稳定性 :
Store at -20 degree C. Stable for 12 months from date of receipt.
检测过的应用 :
Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
应用笔记 :
WB: 1:500-1:1000. IHC: 1; 200. IF/ICC: 1:100-1:500. Important: For Western Blots, incubate membrane with diluted Ab in 5% w/v milk, 1x TBS, 0.1% Tween20 at 4°C with gentle shaking, overnight.
image1头 :
免疫荧光(IF)
image2头 :
免疫组化(免疫组化)
image3头 :
免疫印迹(免疫印迹)
image4头 :
免疫印迹(免疫印迹)
image4描述 :
Western blot analysis of extracts from rat spleen, using MLH3 antibody.
其它信息1 :
Immunogen: A synthesized peptide corresponding to a region within the internal amino acids.
产品描述 :
Function: Probably involved in the repair of mismatches in DNA. Similarity: Belongs to the DNA mismatch repair MutL/HexB family.
NCBI GI登录号 :
91992162
NCBI登录号 :
NP_001035197.1
NCBI基因登录号 :
NM_001040108.1
UniProt数据库登录号 :
Q9UHC1
NCBI分子量 :
164 kD
NCBI信号通路 :
Meiosis Pathway (477133); Meiotic Recombination Pathway (205242); Mismatch Repair Pathway (83045); Mismatch Repair Pathway (453)
NCBI总结 :
This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
Probably involved in the repair of mismatches in DNA.
尺寸1 :
0.1毫升
价格1 :
240美元
尺寸2 :
0.2毫升
价格2 :
280
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。