产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
GSTM2抗体
目录 :
MBS9606997
规格 :
0.1毫升
价格 :
240美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 酶免疫法
更多信息或购买 :
MyBioSource 产品网页
图像
图像 1 :
MyBioSource MBS9606997 图像 1
MBS9606997 at 1/100 staining Mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
图像 2 :
MyBioSource MBS9606997 图像 2
Western blot analysis of Hela whole cell lysates, using GSTM2 Antibody. The lane on the left is treated with the antigen-specific peptide.
产品信息
目录号 :
MBS9606997
产品类型 :
抗体
产品全称 :
GSTM2抗体
产品简称 :
[GSTM2]
产品名称同义词 :
[Glutathione S alkyltransferase M2; Glutathione S aralkyltransferase M2; Glutathione S aryltransferase M2; Glutathione S transferase 4; Glutathione S transferase M1; Glutathione S transferase M2 (muscle); Glutathione S transferase Mu 2 (muscle); Glutathione S transferase Mu 2; Glutathione S-transferase Mu 2; GST class mu 2; GST class-mu 2; GST muscle; GST4; GSTM; GSTM2; GSTM2-2; GSTM2_HUMAN; GTHMUS; MGC117303; S (hydroxyalkyl)glutathione lyase M2]
其他名称 :
[glutathione S-transferase Mu 2 isoform 1; Glutathione S-transferase Mu 2; glutathione S-transferase Mu 2; glutathione S-transferase mu 2; GST class-mu 2; GSTM2-2]
产品基因名称 :
[GSTM2]
其他基因名称 :
[GSTM2;GSTM2;GST4;GSTM;GTHMUS;GSTM2-2;GST4]
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
218
特异性 :
GSTM2抗体检测内生水平总数GSTM2
纯度 :
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
形式 :
液体。 磷酸盐缓冲液, pH值7.4, 150mM氯化钠, 0.02% 叠氮化钠和50% 甘油
浓度 :
1毫克/毫升
储存稳定性 :
Store at -20 degree C. Stable for 12 months from date of receipt.
检测过的应用 :
免疫印迹(免疫印迹), 免疫组化(免疫组化), 酶联免疫吸附测定(EIA)
应用笔记 :
WB: 1:500-1:2000。 IHC: 1:50-1:200
image1头 :
免疫组化(免疫组化)
image2头 :
免疫印迹(免疫印迹)
其它信息1 :
Immunogen: A synthesized peptide derived from human GSTM2, corresponding to a region within C-terminal amino acids.
其他信息2 :
Important: For western blot, incubate membrane with diluted primary Ab in 5% w/v milk , 1X TBS, 0.1% Tween®20 at 4°C with gentle shaking, overnight.
产品描述 :
Description: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. [provided by RefSeq, Jul 2008]. Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Subunit Structure: Homodimer. Similarity: Belongs to the GST superfamily. Mu family.
NCBI GI登录号 :
4504175
NCBI登录号 :
NP_000839.1
NCBI基因登录号 :
NM_000848.3
UniProt数据库登录号 :
P28161
NCBI分子量 :
26 kDa
NCBI信号通路 :
Biological Oxidations Pathway (105698); Chemical Carcinogenesis Pathway (673221); Chemical Carcinogenesis Pathway (673237); Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway (1127639); Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway (1127658); Defective GGT1 Causes Glutathionuria (GLUTH) Pathway (1127659); Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway (1127660); Defective MAT1A Causes Methionine Adenosyltransferase Deficiency (MATD) Pathway (1127663); Defective OPLAH Causes 5-oxoprolinase Deficiency (OPLAHD) Pathway (1127661); Defective SLC35D1 Causes Schneckenbecken Dysplasia (SCHBCKD) Pathway (1127665)
NCBI总结 :
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
尺寸1 :
0.1毫升
价格1 :
240美元
尺寸2 :
0.2毫升
价格2 :
280
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。