产品简要
公司名称 :
NKMAX
产品类型 :
抗体
产品名称 :
人类PD-1抗体
目录 :
APD0811
规格 :
50微升
价格 :
170美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4F12
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名 :
人类PD-1抗体
目录号(SKU号) :
APD0811
NCBI :
AAH74740
描述 :
PD-1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily, also known as Programmed Cell Death 1. It is expressed on activated T cell, B cells, myeloid cells and a subset of thymocytes. PD-1 interacts with expressed PDL1 and PDL2 to inhibit the proliferation and activation of T cells and B cells. Both PDL1 and PDL2 are expressed in a wide variety of normal tissues including heart, lung, placenta, spleen and kidney. PD-1 might be involved in the regulation of peripheral tolerance and may help prevent autoimmune diseases.
别称 :
Programmed cell death 1, CD279, PD1, hPD-1, hPD-l, PDCD1
浓度 :
1mg/ml (determined by BCA assay)
配方 :
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Freeman GJ, et al., (2000) J Exp Med. 192(7):1027-34.;;Latchman Y, et al., (2001) Nat Immunol. 2(3):261-8.;;Nishimura H, HonjoT., (2001) Trends Immunol. 22(5):265-8.;;Okazaki T, et al., (2001) Proc Natl Acad Sci USA. 98(24):13866-71.
ab宿主 :
小鼠
抗体亚型 :
IgG2b kappa
免疫原 :
重组人类PDCD1(21-167aa)纯化来自大肠杆菌
应用 :
酶联免疫吸附测定, 免疫印迹, 免疫细胞化学/IF, 流式细胞仪
IF Comment And Pic :
ICC/IF analysis of PD-1 in HeLa cells. The cell was stained with APD0811 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).
WB Comment and Pic :
The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PD-1 antibody (1:3000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;;Lane 1.: 293T cell lysate;;Lane 2.: Raji cell lysate
反应对象 :
人类
克隆编号 :
4F12
Ab用途 :
The antibody has been tested by ELISA, Western blot, ICC/IF and FACS analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
FACS Comment and Pic :
Flow cytometry analysis of PD-1 in HeLa cell line, staining at 2-5ug for 1x10^6cells (red line). The secondary antibody used goat anti-mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was mouse IgG (black line).
抗原物种 :
人类
基因类别 :
Cancer
共轭 :
未共轭
Clonality Mono VS Poly :
单克隆
Ab纯化评论 :
By protein-G affinity chromatography
产品类型名 :
单克隆抗体
UniProt No. :
Q15116
内部搜索条款 :
PD1, APD0811-10微克, APD0811-20微克, APD0811-50微克, APD0811-100微克, APD0811-250微克, APD0811-500微克, APD0811-1毫克, APD0811-10, APD0811-20, APD0811-50, APD0811-100, APD0811-250, APD0811-500, APD0811-1
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司，制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。