抗体

人类alpha突触核蛋白抗体

ATGA0244

50微升

170美元

单克隆

小鼠

未共轭

AT1E10

免疫印迹, 酶联免疫吸附测定, 免疫细胞化学

人类alpha突触核蛋白抗体

ATGA0244

NP_000336

Alpha-synuclein (amino acids 1-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells.

SNCA, NACP, PARK1, alpha-Synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, Alpha synuclein, Alpha-synuclein isoform NACP140, alphaSYN, MGC105443, MGC110988, MGC127560, MGC64356, Non A beta component of AD amyloid, Non A4 component of amyloid precursor, Non-A-beta component of alzheimers disease amyloid, precursor of PARK 1, PARK 4, PARK4, Parkinson disease familial 1, PD 1, PD1, Synuclein alpha,

1mg/ml (determined by BCA assay)

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Jakes, R., et al. (1994) FEBS lett. 345:27-32. ;; Ueda, K., et al. (1993) Proc. Natl.Acad. Sci. USA 90:11282-11286. ;; Kim, J. (1997) Molecules and Cells 7:78-83.

小鼠

IgG1 kappa

重组人类alpha突触核蛋白(1-140aa)纯化来自大肠杆菌

酶联免疫吸附测定, 免疫印迹, 免疫细胞化学/IF

ICC/IF analysis of alpha-synuclein in LnCap cells. The cell was stained with ATGA0244 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).ICC/IF analysis of alpha-synuclein in HeLa cells. The cell was stained with ATGA0244 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).{ATGA0244-IF2.jpg}

The recombinant human synuclein family (alpha-, beta- and gamma-) proteins (100ng) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human alpha-synuclein antibody (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;;Lane 1.: alpha-synuclein ;;Lane 2.: beta-synuclein ;;Lane 3.: gamma-synuclein

人类

AT1E10

The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

人类

神经科学

未共轭

单克隆

By protein-A affinity chromatography

单克隆抗体

P37840

a-Synuclein,ATGA0244-10ug,ATGA0244-20ug,ATGA0244-50ug,ATGA0244-100ug,ATGA0244-250ug,ATGA0244-500ug,ATGA0244-1mg,ATGA0244-10,ATGA0244-20,ATGA0244-50,ATGA0244-100,ATGA0244-250,ATGA0244-500,ATGA0244-1