产品简要
公司名称 :
NKMAX
产品类型 :
抗体
产品名称 :
人类ING2抗体
目录 :
ATGA0290
规格 :
50微升
价格 :
170美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
AT39E5
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名 :
人类ING2抗体
目录号(SKU号) :
ATGA0290
NCBI :
NP_001555
描述 :
ING2 is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. This protein seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Also, It is component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides.
别称 :
inhibitor of growth protein 2, ING1L, P33ing2
浓度 :
1mg/ml (determined by BCA assay)
配方 :
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Entrez Gene: ING2 inhibitor of growth family, member 2.;; Shimada Y., et al. (1999) Cytogenet Cell Genet 83 (3-4): 232-5.;; Nagashima M., et al. (2001) Proc. Natl. Acad. Sci. U.S.A. 98: 9671-9676.;; Gozani O., et al. (2003) Cell 114: 99-111.;;
ab宿主 :
小鼠
抗体亚型 :
IgG1b kappa
免疫原 :
重组人类ING2(1-280aa)纯化来自大肠杆菌
应用 :
酶联免疫吸附测定, 免疫印迹, 免疫细胞化学/IF
IF Comment And Pic :
ICC/IF analysis of ING2 in Hep3B cells. The cell was stained with ATGA0290 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).
WB Comment and Pic :
The cell lysate of HeLa (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human ING2 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
反应对象 :
人类
克隆编号 :
AT39E5
Ab用途 :
The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
抗原物种 :
人类
基因类别 :
Epigenomics (Transcription & Translation)
共轭 :
未共轭
Clonality Mono VS Poly :
单克隆
Ab纯化评论 :
By protein-A affinity chromatography
产品类型名 :
单克隆抗体
UniProt No. :
Q9H160
内部搜索条款 :
ING2, ATGA0290-10微克, ATGA0290-20微克, ATGA0290-50微克, ATGA0290-100微克, ATGA0290-250微克, ATGA0290-500微克, ATGA0290-1毫克, ATGA0290-10, ATGA0290-20, ATGA0290-50, ATGA0290-100, ATGA0290-250, ATGA0290-500, ATGA0290-1
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司,制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。