产品简要
公司名称 :
NKMAX
产品类型 :
抗体
产品名称 :
Human Layilin/LAYN antibody
目录 :
ATGA0295
规格 :
50微升
价格 :
170美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
AT18E10
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名 :
Human Layilin/LAYN antibody
目录号(SKU号) :
ATGA0295
NCBI :
NP_001245319
描述 :
Layilin is a widely expressed integral membrane hyaluronan receptor and a transmembrane protein with homology to C-type lectins. This protein interacts with the ERM protein family of cytoskeletal membrane linker molecule members, including talin, ezrin, moesin, and radixin. The carboxy-terminal domain of layilin is capable of binding to the amino-terminal domain of radixin. An interdomain interaction between the amino- and the carboxy-terminal domains of radixin inhibits its ability to bind to layilin. Layilin plays an important role in cell adhesion and motility. It is important for the maintenance of the cortical structure in the cell because it mediates signals from the extracellular matrix to the cytoskeleton. In spreading cells, Layilin acts as a membrane-binding site for talin in the peripheral ruffles, and it may play a role in the migration of cells to a wound site.
别称 :
Layilin isoform 1, Layilin
浓度 :
1mg/ml (determined by BCA assay)
配方 :
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Bono P., et al. (2005) Exp Cell Res 1308(1): 177-87.;; Mark L., et al. (1998) The Journal of Cell Biology 143(2): 429.;;
ab宿主 :
小鼠
抗体亚型 :
IgG1 kappa
免疫原 :
重组人类LAYN(22-235aa)纯化来自大肠杆菌
应用 :
酶联免疫吸附测定, 免疫印迹
WB Comment and Pic :
The cell lysate(40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human LAYN antibody (1:3000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;; Lane 1.: A549 cell lysate
反应对象 :
人类
克隆编号 :
AT18E10
Ab用途 :
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
抗原物种 :
人类
基因类别 :
细胞骨架
共轭 :
未共轭
Clonality Mono VS Poly :
单克隆
Ab纯化评论 :
By protein-A affinity chromatography
产品类型名 :
单克隆抗体
UniProt No. :
Q6UX15
内部搜索条款 :
Layilin, LAYN,ATGA0295-10ug,ATGA0295-20ug,ATGA0295-50ug,ATGA0295-100ug,ATGA0295-250ug,ATGA0295-500ug,ATGA0295-1mg,ATGA0295-10,ATGA0295-20,ATGA0295-50,ATGA0295-100,ATGA0295-250,ATGA0295-500,ATGA0295-1
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司，制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。