产品简要
公司名称 :
NKMAX
产品类型 :
抗体
产品名称 :
人类GRP58/PDIA3抗体
目录 :
ATGA0410
规格 :
50微升
价格 :
170美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
AT9E9
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名 :
人类GRP58/PDIA3抗体
目录号(SKU号) :
ATGA0410
NCBI :
NP_005304
描述 :
PDIA3, also known as protein disulfide-isomerase A3, is a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. This protein has protein disulfide isomerase activity. PDIA3 is also part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is essential for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.
别称 :
Protein disulfide isomerase family A member 3, Glucose regulated protein 58kDa, GPR58, Protein disulfide isomerase-associated 3, 58 kDa microsomal protein, P58, ERp61, Endoplasmic reticulum resident protein 57, ER protein 57, ERp57, Disulfide isomerase ER-60, Endoplasmic reticulum resident protein 60, ER protein 60, ERp60, GRP57, PI-PLC, HsT17083
浓度 :
1mg/ml (determined by BCA assay)
配方 :
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Huppa JB., Ploegh HL. (1998) Cell. 92: 145-8.;; Ellgaard L., Ruddock LW. (2005) EMBO Rep. 6: 28-32.;; Jessop CE., et al. (2007) EMBO J. 26: 28-40.;;
ab宿主 :
小鼠
抗体亚型 :
IgG2a kappa
免疫原 :
重组人类PDIA3(25-505aa)纯化来自大肠杆菌
应用 :
酶联免疫吸附测定, 免疫印迹, 免疫细胞化学/IF
IF Comment And Pic :
ICC/IF analysis of PDIA3 in Hep3B cells. The cell was stained with ATGA0410 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).
WB Comment and Pic :
The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PDIA3 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ;;Lane 1. : HeLa cell lysate ;;Lane 2. : HepG2 cell lysate;; Lane 3. : NIH3T3 cell lysate ;;Lane 4. : Raw 264.7 cell lysate;; Lane 5. : LNCaP cell lysate
反应对象 :
人类
克隆编号 :
AT9E9
Ab用途 :
The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
抗原物种 :
人类
基因类别 :
信号转导
共轭 :
未共轭
Clonality Mono VS Poly :
单克隆
Ab纯化评论 :
By protein-A affinity chromatography
产品类型名 :
单克隆抗体
UniProt No. :
P30101
内部搜索条款 :
ERp57, PDIA3, ATGA0410-10微克, ATGA0410-20微克, ATGA0410-50微克, ATGA0410-100微克, ATGA0410-250微克, ATGA0410-500微克, ATGA0410-1毫克, ATGA0410-10, ATGA0410-20, ATGA0410-50, ATGA0410-100, ATGA0410-250, ATGA0410-500, ATGA0410-1
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司,制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。