产品简要
公司名称 :
NKMAX
产品类型 :
抗体
产品名称 :
人类EpCAM/TROP-1抗体
目录 :
ATGA0515
规格 :
50微升
价格 :
170美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
AT36F10
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名 :
人类EpCAM/TROP-1抗体
目录号(SKU号) :
ATGA0515
NCBI :
NP_002345
描述 :
Epithelial cell adhesion molecule (EPCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. EPCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, EPCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since EPCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, EPCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies.
别称 :
上皮细胞 粘连分子, CD326, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1, DIAR5, EGP, GA733 2, HNPCC8
浓度 :
1mg/ml (determined by BCA assay)
配方 :
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Litvinov. Sergey., et al. (1994) The Journal of Cell Biology 125(2): 437-46.;;Maetzel D., et al. (2009) Nat Cell Biol. 11(2): 162-71.;;Osta WA., et al. (2004) Cancer Res. 64(16): 5818-24.;;Munz M., et al. (2004) Oncogene 23(34): 5748-58.;;Armstrong A., et al. (2003) Cancer Biol Ther, 2(4): 320-6.
ab宿主 :
小鼠
抗体亚型 :
IgG2b kappa
免疫原 :
重组人类EpCAM/TROP-1(24-265aa)纯化来自大肠杆菌
应用 :
酶联免疫吸附测定, 免疫印迹, 免疫细胞化学/IF
IF Comment And Pic :
ICC/IF analysis of EpCAM/TROP-1 in A431 cells. The cell was stained with ATGA0515 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).
WB Comment and Pic :
The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human EpCAM/TROP-1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;;Lane 1.: MCF7 cell lysate;;Lane 2.: PC3 cell lysate;;Lane 3.: HeLa cell lysate
反应对象 :
人类
克隆编号 :
AT36F10
Ab用途 :
The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
抗原物种 :
人类
基因类别 :
标签&细胞标记
共轭 :
未共轭
Clonality Mono VS Poly :
单克隆
Ab纯化评论 :
By protein-A affinity chromatography
产品类型名 :
单克隆抗体
UniProt No. :
P16422
内部搜索条款 :
EpCAM, TROP1, ATGA0515-10微克, ATGA0515-20微克, ATGA0515-50微克, ATGA0515-100微克, ATGA0515-250微克, ATGA0515-500微克, ATGA0515-1毫克, ATGA0515-10, ATGA0515-20, ATGA0515-50, ATGA0515-100, ATGA0515-250, ATGA0515-500, ATGA0515-1
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司,制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。